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Protein

Guanylate kinase

Gene

gmk

Organism
Pseudomonas fluorescens (strain Pf0-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPFLU205922:G1G4S-5666-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:Pfl01_5549
OrganismiPseudomonas fluorescens (strain Pf0-1)
Taxonomic identifieri205922 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002704 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002663721 – 206Guanylate kinaseAdd BLAST206

Proteomic databases

PRIDEiQ3K4L8

Interactioni

Protein-protein interaction databases

STRINGi205922.Pfl01_5549

Structurei

3D structure databases

ProteinModelPortaliQ3K4L8
SMRiQ3K4L8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 184Guanylate kinase-likeUniRule annotationAdd BLAST179

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037638
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q3K4L8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHSTGTLYI ISAPSGAGKS SLVKALTDTN PDIRVSISHT TRAMRPGEVD
60 70 80 90 100
GVNYHFVTRE EFVKMGEHGD FLERAEVFGN FYGTSQSRLQ QTLDEGHDLI
110 120 130 140 150
LEIDWQGAEQ VRKLMPQARS IFILPPSLQA LHQRLTNRGQ DSDEIIDGRM
160 170 180 190 200
REAVSEMSHY VEYDYLIIND DFAHALDDLK AIFRANQLQQ KRQQVRFGKL

LAELLG
Length:206
Mass (Da):23,347
Last modified:November 8, 2005 - v1
Checksum:i020EF8B7B58AB162
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000094 Genomic DNA Translation: ABA77286.1
RefSeqiWP_011336561.1, NC_007492.2

Genome annotation databases

EnsemblBacteriaiABA77286; ABA77286; Pfl01_5549
KEGGipfo:Pfl01_5549

Similar proteinsi

Entry informationi

Entry nameiKGUA_PSEPF
AccessioniPrimary (citable) accession number: Q3K4L8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: November 8, 2005
Last modified: March 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health