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Q3K2D9

- WHIA_STRA1

UniProt

Q3K2D9 - WHIA_STRA1

Protein

Putative sporulation transcription regulator WhiA

Gene

whiA

Organism
Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    May be required for sporulation.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi272 – 30332H-T-H motifUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. endonuclease activity Source: InterPro

    GO - Biological processi

    1. regulation of sporulation Source: UniProtKB-HAMAP
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciSAGA205921:GHD7-684-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative sporulation transcription regulator WhiAUniRule annotation
    Gene namesi
    Name:whiAUniRule annotation
    Ordered Locus Names:SAK_0683
    OrganismiStreptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
    Taxonomic identifieri205921 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000002701: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 303303Putative sporulation transcription regulator WhiAPRO_0000376570Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi205921.SAK_0683.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the WhiA transcriptional regulatory family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1481.
    HOGENOMiHOG000040187.
    KOiK09762.
    OMAiHKFMLDA.
    OrthoDBiEOG68WR87.

    Family and domain databases

    Gene3Di3.10.28.10. 1 hit.
    HAMAPiMF_01420. HTH_type_WhiA.
    InterProiIPR027434. Homing_endonucl.
    IPR018478. Sporu_reg_WhiA_N_dom.
    IPR003802. Sporulation_regulator_WhiA.
    IPR023054. Sporulation_regulator_WhiA_C.
    [Graphical view]
    PfamiPF02650. HTH_WhiA. 1 hit.
    PF10298. WhiA_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF55608. SSF55608. 1 hit.
    TIGRFAMsiTIGR00647. MG103. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3K2D9-1 [UniParc]FASTAAdd to Basket

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    MSFTVKVKEE LLGHKSENKM ELSAIIKMSG SLGLANHGLN LSITTENAKI    50
    ARHIYSMLEE HYHLQPEIKY HQKTNLRKNR VYTVFIEEKV DVILADLKLA 100
    DAFFGIETGI EHSILDNDEN GRAYLRGAFL STGTVREPDS GKYQLEIFSV 150
    YLDHAQDLAN LMKKFMLDAK VIEHKHGAVT YLQKAEDIMD FLIVIDAMEA 200
    RDAFEEIKMI RETRNDINRA NNVETANIAR TITASMKTIN NIIKIMDTIG 250
    FDALPSDLRQ VAQVRVAHPD YSIQQIADSL ETPLSKSGVN HRLRKINKIA 300
    DEL 303
    Length:303
    Mass (Da):34,381
    Last modified:November 8, 2005 - v1
    Checksum:iDB494200EBB4FD39
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000114 Genomic DNA. Translation: ABA46160.1.
    RefSeqiYP_329314.1. NC_007432.1.

    Genome annotation databases

    EnsemblBacteriaiABA46160; ABA46160; SAK_0683.
    GeneIDi3686603.
    KEGGisak:SAK_0683.
    PATRICi19632605. VBIStrAga82541_0613.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000114 Genomic DNA. Translation: ABA46160.1 .
    RefSeqi YP_329314.1. NC_007432.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 205921.SAK_0683.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABA46160 ; ABA46160 ; SAK_0683 .
    GeneIDi 3686603.
    KEGGi sak:SAK_0683.
    PATRICi 19632605. VBIStrAga82541_0613.

    Phylogenomic databases

    eggNOGi COG1481.
    HOGENOMi HOG000040187.
    KOi K09762.
    OMAi HKFMLDA.
    OrthoDBi EOG68WR87.

    Enzyme and pathway databases

    BioCyci SAGA205921:GHD7-684-MONOMER.

    Family and domain databases

    Gene3Di 3.10.28.10. 1 hit.
    HAMAPi MF_01420. HTH_type_WhiA.
    InterProi IPR027434. Homing_endonucl.
    IPR018478. Sporu_reg_WhiA_N_dom.
    IPR003802. Sporulation_regulator_WhiA.
    IPR023054. Sporulation_regulator_WhiA_C.
    [Graphical view ]
    Pfami PF02650. HTH_WhiA. 1 hit.
    PF10298. WhiA_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55608. SSF55608. 1 hit.
    TIGRFAMsi TIGR00647. MG103. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial 'pan-genome'."
      Tettelin H., Masignani V., Cieslewicz M.J., Donati C., Medini D., Ward N.L., Angiuoli S.V., Crabtree J., Jones A.L., Durkin A.S., DeBoy R.T., Davidsen T.M., Mora M., Scarselli M., Margarit y Ros I., Peterson J.D., Hauser C.R., Sundaram J.P.
      , Nelson W.C., Madupu R., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sullivan S.A., Daugherty S.C., Haft D.H., Selengut J., Gwinn M.L., Zhou L., Zafar N., Khouri H., Radune D., Dimitrov G., Watkins K., O'Connor K.J., Smith S., Utterback T.R., White O., Rubens C.E., Grandi G., Madoff L.C., Kasper D.L., Telford J.L., Wessels M.R., Rappuoli R., Fraser C.M.
      Proc. Natl. Acad. Sci. U.S.A. 102:13950-13955(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27591 / A909 / CDC SS700.

    Entry informationi

    Entry nameiWHIA_STRA1
    AccessioniPrimary (citable) accession number: Q3K2D9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 26, 2009
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3