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Protein

Putative sporulation transcription regulator WhiA

Gene

whiA

Organism
Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be required for sporulation.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi272 – 30332H-T-H motifUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSAGA205921:GHD7-684-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sporulation transcription regulator WhiAUniRule annotation
Gene namesi
Name:whiAUniRule annotation
Ordered Locus Names:SAK_0683
OrganismiStreptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
Taxonomic identifieri205921 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002701 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Putative sporulation transcription regulator WhiAPRO_0000376570Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi205921.SAK_0683.

Family & Domainsi

Sequence similaritiesi

Belongs to the WhiA transcriptional regulatory family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1481.
HOGENOMiHOG000040187.
KOiK09762.
OMAiHKFMLDA.
OrthoDBiEOG68WR87.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3K2D9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFTVKVKEE LLGHKSENKM ELSAIIKMSG SLGLANHGLN LSITTENAKI
60 70 80 90 100
ARHIYSMLEE HYHLQPEIKY HQKTNLRKNR VYTVFIEEKV DVILADLKLA
110 120 130 140 150
DAFFGIETGI EHSILDNDEN GRAYLRGAFL STGTVREPDS GKYQLEIFSV
160 170 180 190 200
YLDHAQDLAN LMKKFMLDAK VIEHKHGAVT YLQKAEDIMD FLIVIDAMEA
210 220 230 240 250
RDAFEEIKMI RETRNDINRA NNVETANIAR TITASMKTIN NIIKIMDTIG
260 270 280 290 300
FDALPSDLRQ VAQVRVAHPD YSIQQIADSL ETPLSKSGVN HRLRKINKIA

DEL
Length:303
Mass (Da):34,381
Last modified:November 8, 2005 - v1
Checksum:iDB494200EBB4FD39
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000114 Genomic DNA. Translation: ABA46160.1.
RefSeqiWP_000011316.1. NC_007432.1.
YP_329314.1. NC_007432.1.

Genome annotation databases

EnsemblBacteriaiABA46160; ABA46160; SAK_0683.
KEGGisak:SAK_0683.
PATRICi19632605. VBIStrAga82541_0613.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000114 Genomic DNA. Translation: ABA46160.1.
RefSeqiWP_000011316.1. NC_007432.1.
YP_329314.1. NC_007432.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi205921.SAK_0683.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA46160; ABA46160; SAK_0683.
KEGGisak:SAK_0683.
PATRICi19632605. VBIStrAga82541_0613.

Phylogenomic databases

eggNOGiCOG1481.
HOGENOMiHOG000040187.
KOiK09762.
OMAiHKFMLDA.
OrthoDBiEOG68WR87.

Enzyme and pathway databases

BioCyciSAGA205921:GHD7-684-MONOMER.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial 'pan-genome'."
    Tettelin H., Masignani V., Cieslewicz M.J., Donati C., Medini D., Ward N.L., Angiuoli S.V., Crabtree J., Jones A.L., Durkin A.S., DeBoy R.T., Davidsen T.M., Mora M., Scarselli M., Margarit y Ros I., Peterson J.D., Hauser C.R., Sundaram J.P.
    , Nelson W.C., Madupu R., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sullivan S.A., Daugherty S.C., Haft D.H., Selengut J., Gwinn M.L., Zhou L., Zafar N., Khouri H., Radune D., Dimitrov G., Watkins K., O'Connor K.J., Smith S., Utterback T.R., White O., Rubens C.E., Grandi G., Madoff L.C., Kasper D.L., Telford J.L., Wessels M.R., Rappuoli R., Fraser C.M.
    Proc. Natl. Acad. Sci. U.S.A. 102:13950-13955(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27591 / A909 / CDC SS700.

Entry informationi

Entry nameiWHIA_STRA1
AccessioniPrimary (citable) accession number: Q3K2D9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: November 8, 2005
Last modified: May 27, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.