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Q3K1U4 (EFTU_STRA1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Elongation factor Tu
Short name=EF-Tu
Gene names
Name:tuf
Ordered Locus Names:SAK_0887
OrganismStreptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700) [Complete proteome] [HAMAP]
Taxonomic identifier205921 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus ›

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processGTP catabolic process

Inferred from electronic annotation. Source: GOC

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Elongation factor Tu HAMAP-Rule MF_00118
PRO_1000015755

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding84 – 885GTP By similarity
Nucleotide binding139 – 1424GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3K1U4 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 362988E2DAB0E1EE

FASTA39843,982
        10         20         30         40         50         60 
MAKEKYDRSK PHVNIGTIGH VDHGKTTLTA AITTVLARRL PTSVNQPKDY ASIDAAPEER 

        70         80         90        100        110        120 
ERGITINTAH VEYETEKRHY AHIDAPGHAD YVKNMITGAA QMDGAILVVA STDGPMPQTR 

       130        140        150        160        170        180 
EHILLSRQVG VKHLIVFMNK VDLVDDEELL ELVEMEIRDL LSEYDFPGDD LPVIQGSALK 

       190        200        210        220        230        240 
ALEGDEKYED IIMELMSTVD EYIPEPERDT DKPLLLPVED VFSITGRGTV ASGRIDRGTV 

       250        260        270        280        290        300 
RVNDEVEIVG IKEDIQKAVV TGVEMFRKQL DEGLAGDNVG VLLRGVQRDE IERGQVLAKP 

       310        320        330        340        350        360 
GSINPHTKFK GEVYILSKEE GGRHTPFFNN YRPQFYFRTT DVTGSIELPA GTEMVMPGDN 

       370        380        390 
VTIEVELIHP IAVEQGTTFS IREGGRTVGS GIVSEIEA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000114 Genomic DNA. Translation: ABA45463.1.
RefSeqYP_329509.1. NC_007432.1.

3D structure databases

HSSPHSSP built from PDB template 2BVN based on UniProtKB P0A6N1.
ProteinModelPortalQ3K1U4.
SMRQ3K1U4. Positions 2-396.
ModBaseSearch...

Protein-protein interaction databases

STRING205921.SAK_0887.

PTM databases

PhosSiteP12051535.

Proteomic databases

PRIDEQ3K1U4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA45463; ABA45463; SAK_0887.
GeneID3685598.
KEGGsak:SAK_0887.
PATRIC19633037. VBIStrAga82541_0828.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMAHTDFEAN.
ProtClustDBPRK12736.

Enzyme and pathway databases

BioCycSAGA205921:GHD7-903-MONOMER.

Family and domain databases

HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR005225. Small_GTP-bd_dom.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
IPR009000. Transl_elong_init/rib_B-barrel.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50465. Elong_init_C. 1 hit.
SSF50447. Translat_factor. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_STRA1
AccessionPrimary (citable) accession number: Q3K1U4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 8, 2005
Last modified: May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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