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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei300NucleophileUniRule annotation1
Active sitei351Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

UniPathwayiUPA00164

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:SAK_0976
OrganismiStreptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
Taxonomic identifieri205921 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002607041 – 6221,4-alpha-glucan branching enzyme GlgBAdd BLAST622

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ3K1K5
SMRiQ3K1K5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000283037
KOiK00700
OMAiEVVHGKS

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.1180, 1 hit
HAMAPiMF_00685 GlgB, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006407 GlgB
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 1 hit
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR01515 branching_enzym, 1 hit

Sequencei

Sequence statusi: Complete.

Q3K1K5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNKDELYTF GIGENFHLQN YLGVHSENGS FCFRVWAPNA ENVQVIGDFT
60 70 80 90 100
DWRNRPLQMN KNQAGVWEAN SLDAREGDLY KYLVTRKGGQ VVEKIDPMAV
110 120 130 140 150
YMERRPGTAS VIKVLRNKKW EDGLWMGRRK RLGFQKRPIN IYEVHAGSWK
160 170 180 190 200
KDDFGHPMTF SQLKDYLIPY LVEMNYTHVE FMPLMAHPLD MSWGYQLMGY
210 220 230 240 250
FAFEHTYGTP EEFQDFVEAC HKNNIGVLVD WVPGHFIQND DALAYFDGTA
260 270 280 290 300
TYEYQNHDRA HNYRWGALNF DLGKNQVQSF LISSALFWIE HYHIDGIRVD
310 320 330 340 350
AVSNMLYLDY DEGPWEANQF GDNRNLEGYH FLRKLNKVIK ERHPNVMMIA
360 370 380 390 400
EESTASTPIT KDLESGGLGF DFKWNMGWMN DILRFYEEDP LYRQYDFNLV
410 420 430 440 450
TFSFMYIFNE NFVLAFSHDE VVHGKKSMMH KMWGDRYNQF AGLRNLYAYQ
460 470 480 490 500
MCHPGKKLLF MGSEFGQFLE WKYNDQLEWE NLNDDMNQKM QRYTKQLNQF
510 520 530 540 550
YKDHKCLWRI DDSFDGLEII DADNKSETVL SFIRKDDKGD LLLCVFNMTP
560 570 580 590 600
VERPNFTIGV PQAGIYEEVL NTEMEEFGGV WKNHNPVTKT QVATWKDYDH
610 620
TLSFTLPALG ASVWRIKRRL RK
Length:622
Mass (Da):73,342
Last modified:November 8, 2005 - v1
Checksum:i9533F1F3EADB5D26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000114 Genomic DNA Translation: ABA44706.1
RefSeqiWP_000066082.1, NC_007432.1

Genome annotation databases

EnsemblBacteriaiABA44706; ABA44706; SAK_0976
KEGGisak:SAK_0976

Similar proteinsi

Entry informationi

Entry nameiGLGB_STRA1
AccessioniPrimary (citable) accession number: Q3K1K5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 8, 2005
Last modified: February 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health