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Q3K1K2

- GLGA_STRA1

UniProt

Q3K1K2 - GLGA_STRA1

Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

    Catalytic activityi

    ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei15 – 151ADP-glucoseUniRule annotation

    GO - Molecular functioni

    1. starch synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Glycogen biosynthesis

    Enzyme and pathway databases

    BioCyciSAGA205921:GHD7-980-MONOMER.
    UniPathwayiUPA00164.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
    Alternative name(s):
    Starch [bacterial glycogen] synthaseUniRule annotation
    Gene namesi
    Name:glgAUniRule annotation
    Ordered Locus Names:SAK_0979
    OrganismiStreptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
    Taxonomic identifieri205921 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000002701: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 476476Glycogen synthasePRO_0000230266Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi205921.SAK_0979.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3K1K2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0297.
    HOGENOMiHOG000294940.
    KOiK00703.
    OMAiPYHDESQ.
    OrthoDBiEOG6JTC6Z.

    Family and domain databases

    HAMAPiMF_00484. Glycogen_synth.
    InterProiIPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view]
    PfamiPF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02095. glgA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3K1K2-1 [UniParc]FASTAAdd to Basket

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    MKIMFVAAEG APFAKTGGLG DVIGALPKSL SKKGHDVAVV MPYYDMVDQK    50
    FGDQIENLMY FYTDVGWRHQ YVGVKRLSQD NVTFYFIDNQ YYFYRGHVYG 100
    DWDDGERFAY FQLAALELME KIDFIPDVLH VHDYHTAMIP FLLKEKYHWI 150
    QAYNNIRAVF TIHNIEFQGQ FGPEMLGDLF GVGAERYEDG TLRWNNCLNW 200
    MKAAILYSDR VTTVSPSYAN EIKTPEFGKG LDQIMRMEAG KLSGIVNGID 250
    SDLLNPETDA FLPYHFSKSN LEGKIKNKLA LQENLGLPQD KNVPLIGIVS 300
    RLTDQKGFDI IASELDNMLQ QDIQMVILGT GYHHFEETFS YFASRYPEKL 350
    SANITFDLRL AQQIYAASDI FMMPSAFEPC GLSQMMAMRY GSLPLVHEVG 400
    GLKDTVVAFN QFDGSGTGFS FNHFSGYWLM QTLKLALEVY NDYPEAWKKL 450
    QWQAMSKDFS WDTACVAYEQ LYQQLQ 476
    Length:476
    Mass (Da):54,514
    Last modified:November 8, 2005 - v1
    Checksum:i2E0F259CE9F4CF8D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000114 Genomic DNA. Translation: ABA45078.1.
    RefSeqiYP_329601.1. NC_007432.1.

    Genome annotation databases

    EnsemblBacteriaiABA45078; ABA45078; SAK_0979.
    GeneIDi3685649.
    KEGGisak:SAK_0979.
    PATRICi19633223. VBIStrAga82541_0921.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000114 Genomic DNA. Translation: ABA45078.1 .
    RefSeqi YP_329601.1. NC_007432.1.

    3D structure databases

    ProteinModelPortali Q3K1K2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 205921.SAK_0979.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABA45078 ; ABA45078 ; SAK_0979 .
    GeneIDi 3685649.
    KEGGi sak:SAK_0979.
    PATRICi 19633223. VBIStrAga82541_0921.

    Phylogenomic databases

    eggNOGi COG0297.
    HOGENOMi HOG000294940.
    KOi K00703.
    OMAi PYHDESQ.
    OrthoDBi EOG6JTC6Z.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .
    BioCyci SAGA205921:GHD7-980-MONOMER.

    Family and domain databases

    HAMAPi MF_00484. Glycogen_synth.
    InterProi IPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view ]
    Pfami PF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02095. glgA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial 'pan-genome'."
      Tettelin H., Masignani V., Cieslewicz M.J., Donati C., Medini D., Ward N.L., Angiuoli S.V., Crabtree J., Jones A.L., Durkin A.S., DeBoy R.T., Davidsen T.M., Mora M., Scarselli M., Margarit y Ros I., Peterson J.D., Hauser C.R., Sundaram J.P.
      , Nelson W.C., Madupu R., Brinkac L.M., Dodson R.J., Rosovitz M.J., Sullivan S.A., Daugherty S.C., Haft D.H., Selengut J., Gwinn M.L., Zhou L., Zafar N., Khouri H., Radune D., Dimitrov G., Watkins K., O'Connor K.J., Smith S., Utterback T.R., White O., Rubens C.E., Grandi G., Madoff L.C., Kasper D.L., Telford J.L., Wessels M.R., Rappuoli R., Fraser C.M.
      Proc. Natl. Acad. Sci. U.S.A. 102:13950-13955(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27591 / A909 / CDC SS700.

    Entry informationi

    Entry nameiGLGA_STRA1
    AccessioniPrimary (citable) accession number: Q3K1K2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3