Q3JXT0 (PHS_BURP1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase
Short name=PHS
EC=4.2.1.96

Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name=PCD

Gene names

Ordered Locus Names:

BURPS1710b_0207

Organism

Burkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP]

Taxonomic identifier

320372 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Sequence caution	The sequence ABA47754.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 101	101	Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434		PRO_0000231445

Sequences

	Sequence		Length	Mass (Da)
	Q3JXT0 [UniParc]. Last modified April 4, 2006. Version 2. Checksum: 7B7B98F607C62FDC	FASTA	101	11,681
	10 20 30 40 50 60 MIHKLTSEER KTQLESLHHW TAVPGRDAIQ RSLRFADFNE AFGFMTRVAI KAQEMNHHPE 70 80 90 100 WFNVYNRVDV TLSTHDANGL TERDIKLAHF IDEVGKHAKA A

References

[1]	Woods D.E., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1710b.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000124 Genomic DNA. Translation: ABA47754.1. Different initiation.
RefSeq	YP_331623.1. NC_007434.1.
3D structure databases
ProteinModelPortal	Q3JXT0.
SMR	Q3JXT0. Positions 3-96.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3JXT0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3689505.
GenomeReviews	Gene locus BURPS1710b_0207 in contig CP000124_GR.
KEGG	bpm:BURPS1710b_0207.
PATRIC	19232618. VBIBurPse115837_0202.
TIGR	BURPS1710b_0207.
Phylogenomic databases
eggNOG	COG2154.
HOGENOM	HBG705804.
PhylomeDB	Q3JXT0.
ProtClustDB	PRK00823.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
KO	K01724.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
SUPFAM	SSF55248. Trans_pterinDh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PHS_BURP1

Accession

Primary (citable) accession number: Q3JXT0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	April 4, 2006
Last modified:	January 25, 2012
This is version 31 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program