ID   Q3JWM8_BURP1            Unreviewed;       682 AA.
AC   Q3JWM8;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   SubName: Full=2`,3`-cyclic-nucleotide 2`-phosphodiesterase {ECO:0000313|EMBL:ABA48941.1};
DE            EC=3.1.4.16 {ECO:0000313|EMBL:ABA48941.1};
GN   Name=cpdB {ECO:0000313|EMBL:ABA48941.1};
GN   OrderedLocusNames=BURPS1710b_0611 {ECO:0000313|EMBL:ABA48941.1};
OS   Burkholderia pseudomallei (strain 1710b).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=320372 {ECO:0000313|EMBL:ABA48941.1, ECO:0000313|Proteomes:UP000002700};
RN   [1] {ECO:0000313|EMBL:ABA48941.1, ECO:0000313|Proteomes:UP000002700}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1710b {ECO:0000313|EMBL:ABA48941.1,
RC   ECO:0000313|Proteomes:UP000002700};
RA   Woods D.E., Nierman W.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the 5'-nucleotidase family.
CC       {ECO:0000256|ARBA:ARBA00006654, ECO:0000256|RuleBase:RU362119}.
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DR   EMBL; CP000124; ABA48941.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q3JWM8; -.
DR   EnsemblBacteria; ABA48941; ABA48941; BURPS1710b_0611.
DR   KEGG; bpm:BURPS1710b_0611; -.
DR   HOGENOM; CLU_005854_4_1_4; -.
DR   Proteomes; UP000002700; Chromosome I.
DR   GO; GO:0008663; F:2',3'-cyclic-nucleotide 2'-phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008252; F:nucleotidase activity; IEA:UniProt.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR   Gene3D; 3.60.21.10; -; 1.
DR   Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR   InterPro; IPR008334; 5'-Nucleotdase_C.
DR   InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR   InterPro; IPR006146; 5'-Nucleotdase_CS.
DR   InterPro; IPR006179; 5_nucleotidase/apyrase.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR11575:SF6; 2',3'-CYCLIC-NUCLEOTIDE 2'-PHOSPHODIESTERASE_3'-NUCLEOTIDASE; 1.
DR   PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR   Pfam; PF02872; 5_nucleotid_C; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   PRINTS; PR01607; APYRASEFAMLY.
DR   SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR   PROSITE; PS00786; 5_NUCLEOTIDASE_2; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|RuleBase:RU362119, ECO:0000313|EMBL:ABA48941.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362119};
KW   Signal {ECO:0000256|RuleBase:RU362119}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|RuleBase:RU362119"
FT   CHAIN           23..682
FT                   /evidence="ECO:0000256|RuleBase:RU362119"
FT                   /id="PRO_5005143150"
FT   DOMAIN          47..304
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
FT   DOMAIN          464..590
FT                   /note="5'-Nucleotidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02872"
SQ   SEQUENCE   682 AA;  72380 MW;  44B028C048075C6D CRC64;
     MRFRRRRLAA ALVACAALVA GCNDDVDSPG AQSGASAPAG TKATLAVLET TDLHTNVLSY
     DYFKLAADKS LGFERVATLI AQARAQYPNT LLLDNGDTIQ GTALADYQAL VKPVSCGETL
     AIYKVMNAAK FDGGGIGNHE FNYGLPYLSQ VTGNAFAVDG LPDPARQKKC AGPDFPQVLA
     NVISAKTNAP LFTPYTILTK NVTATTPDGR TVTAPVKVGI IGFTPPAIMS WDKRWLDGKV
     YTTGLKEAAE KYIPEMRAKG ADLVVAISHG GLDNSPYSPT MENGSWWLST VPGIDAMLIG
     HSHQVFPDAT STVAQFNLPG VDKVKGTVNG VPTVMANYWG KHLGVIKLGL AFDGKTWRVD
     KSQTTVEARS IQNPDKSYVD ADPSVAAAIA AEHQATIDYV KTPIGSTDYR MTSYFADVGD
     PGAIQLVNEA QADYVANYVQ TNLPQYASLP VLSVSAPFKS GFGGGTDFTD VAAGALAINN
     AADLYLYPNT VYAVKVSGAD IKNWLETAAK RFNTIDPTKA TVQKLVSTFP GYNFDMFTSA
     DLRYEIDVTQ PAGSRIRNLA YKGAPIDPNA QFIVATNNYR ASGGGNFPGL DGSKTIFASP
     DANRDVLIAY IKKRGRITRA ADGMQRSWRF TKLAGSVAHV QFASAPNLAA LASTAGLAGI
     TQVAADDGSG KGLATYEIDL TQ
//