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Q3JW86 (Q3JW86_BURP1) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribose-phosphate pyrophosphokinase HAMAP-Rule MF_00583
Short name=RPPK HAMAP-Rule MF_00583
EC=2.7.6.1 HAMAP-Rule MF_00583
Alternative name(s):
Phosphoribosyl pyrophosphate synthase HAMAP-Rule MF_00583
Gene names
Name:prsA EMBL ABA50338.1
Synonyms:prs HAMAP-Rule MF_00583
Ordered Locus Names:BURPS1710b_0753
OrganismBurkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP] EMBL ABA50338.1
Taxonomic identifier320372 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group ›

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00583 RuleBase RU004325

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_00583

Pathway

Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. HAMAP-Rule MF_00583

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00583.

Sequence similarities

Belongs to the ribose-phosphate pyrophosphokinase family. HAMAP-Rule MF_00583 RuleBase RU004324

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region215 – 228145-phosphoribose 1-diphosphate binding By similarity HAMAP-Rule MF_00583

Sites

Metal binding1321Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1341Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1431Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1471Magnesium By similarity HAMAP-Rule MF_00583

Sequences

Sequence LengthMass (Da)Tools
Q3JW86 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 610A0423F8988DA7

FASTA31834,211
        10         20         30         40         50         60 
MSSHDGLMVF TGNANPALAQ EVVKILGIPL GKAMVSRFSD GEIQVEIQEN VRGKDVFVLQ 

        70         80         90        100        110        120 
STCAPTNDNL MELMIMVDAL KRASAGRITA AIPYFGYARQ DRRPRSARVA ISAKVVANML 

       130        140        150        160        170        180 
EIAGVERIIT MDLHADQIQG FFDIPVDNIY ATPILLGDLR KQNYPDLLVV SPDVGGVVRA 

       190        200        210        220        230        240 
RALAKQLNCD LAIIDKRRPK ANVAEVMNII GEVEGRTCVI MDDMVDTAGT LCKAAQVLKE 

       250        260        270        280        290        300 
RGAKQVFAYA THPVLSGGAA DRIAASALDE LVVTDTIPLS AESLACPKIR ALSSAGLLAE 

       310 
TFSRIRRGDS VMSLFAES

« Hide

References

[1]Woods D.E., Nierman W.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1710b EMBL ABA50338.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000124 Genomic DNA. Translation: ABA50338.1.
RefSeqYP_332167.1. NC_007434.1.

3D structure databases

ProteinModelPortalQ3JW86.
SMRQ3JW86. Positions 7-316.
ModBaseSearch...

Protein-protein interaction databases

STRING320372.BURPS1710b_0753.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA50338; ABA50338; BURPS1710b_0753.
GeneID3690278.
KEGGbpm:BURPS1710b_0753.
PATRIC19233744. VBIBurPse115837_0763.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0462.
HOGENOMHOG000210452.
KOK00948.
OMATRISPTE.
ProtClustDBPRK01259.

Enzyme and pathway databases

UniPathwayUPA00087; UER00172.

Family and domain databases

HAMAPMF_00583_B. RibP_PPkinase_B.
InterProIPR000842. PRib_PP_synth_CS.
IPR000836. PRibTrfase_dom.
IPR005946. Rib-P_diPkinase.
[Graphical view]
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01251. ribP_PPkin. 1 hit.
PROSITEPS00114. PRPP_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ3JW86_BURP1
AccessionPrimary (citable) accession number: Q3JW86
Entry history
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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