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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia pseudomallei (strain 1710b)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei295UniRule annotation1
Active sitei737UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:BURPS1710b_1228Imported
OrganismiBurkholderia pseudomallei (strain 1710b)Imported
Taxonomic identifieri320372 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000002700 Componenti: Chromosome I

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q3JUW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPARPPGGLR ERPVRSASRS RTAVRFEKAS GIRQRVRFAA ASPAASFAAS
60 70 80 90 100
SGFIVRRASP AVRHAPPRRL IAPAVAGPQF PFTRAFPRKS IVKSSGSARA
110 120 130 140 150
TRRNAVSSSS APAHAEPPAR RAAKPARKLD GAAARPLAPT NAASAKPQGR
160 170 180 190 200
TREDKDRPLF EDIRYLGRLL GDVVREQEGD AVFDVVETIR QTAVKFRRED
210 220 230 240 250
DKAAAQTLEK MLRKLTPEQT VSVVRAFSYF SHLANIAEDR HHNRRRRIHA
260 270 280 290 300
LAGSAAQAGT VAYALDKLKQ AGDASSKTIK QFFEGALIVP VLTAHPTEVQ
310 320 330 340 350
RKSILDAQHD IARLLAERDQ PLTARELAHN EALLRARVTT LWQTRMLRDA
360 370 380 390 400
RLTVADEIEN ALSYYRATFL DELPALYADI EEALAEHGLR ARVPAFFQMG
410 420 430 440 450
SWIGGDRDGN PNVTAATLDE AISRQAAVIF EHYLEQVHKL GAELSVSNLL
460 470 480 490 500
VGASDALKAL AAASPDQSPH RVDEPYRRAL IGVYTRLAAS ARVRLGEGTV
510 520 530 540 550
PVRSAGRGAA PVRATPYADA EEFAADLRVL TDSLALHHGE SLATPRLAPL
560 570 580 590 600
MRAAEVFGFH LASIDLRQSS DIHEAVVAEL LARGGVEADY AALPEADKLR
610 620 630 640 650
VLLAALADPR PLRSPYLDYS DLAKSELGVL ERAHAIRAQF GARAVRNYII
660 670 680 690 700
SHTETVSDLV EVLLLQKETG LFEGTLGTPH ANARNGLMVI PLFETIADLR
710 720 730 740 750
NASDIMRAFF ALPGVGELLA HQGHEQEVML GYSDSNKDGG FLTSNWELYR
760 770 780 790 800
AELALVDLFD ERGIKLRLFH GRGGTVGRGG GPTYQAILSQ PPGTVNGQIR
810 820 830 840 850
LTEQGEVIAS KFANPEIGRR NLETVVAATL EATLAPHSNA PKQLPAFEAT
860 870 880 890 900
MQTLSDAAMA SYRALVYETP GFTDYFFSST PITEIAELNI GSRPASRKLQ
910 920 930 940 950
DPKNRKIEDL RAIPWGFSWG QCRLLLTGWY GFGSAVAAYL DGAPDAAERG
960 970 980 990 1000
KRVALLKKMN KTWPFFANLL SNMDMVLAKT DLAVASRYAQ LVADKKLRKH
1010 1020 1030 1040 1050
VFERIVAEWH RTADALAEIT GAHARLAANP LLARSIKNRF PYLDPLNHLQ
1060 1070 1080
VELIKRHRAG DTNARLRRGI HLTINGIAAG LRNTG
Length:1,085
Mass (Da):118,534
Last modified:November 8, 2005 - v1
Checksum:iCE291E377FBD2DAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000124 Genomic DNA Translation: ABA49199.1

Genome annotation databases

EnsemblBacteriaiABA49199; ABA49199; BURPS1710b_1228
KEGGibpm:BURPS1710b_1228

Similar proteinsi

Entry informationi

Entry nameiQ3JUW4_BURP1
AccessioniPrimary (citable) accession number: Q3JUW4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health