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Q3JRF0 (MSRB_BURP1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrB
EC=1.8.4.12
Alternative name(s):
Peptide-methionine (R)-S-oxide reductase
Gene names
Name:msrB
Ordered Locus Names:BURPS1710b_2458
OrganismBurkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP]
Taxonomic identifier320372 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length143 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400

Cofactor

Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

Sequence similarities

Belongs to the MsrB Met sulfoxide reductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 143143Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
PRO_0000338617

Sites

Active site1281Nucleophile By similarity
Metal binding551Zinc
Metal binding581Zinc
Metal binding1041Zinc
Metal binding1071Zinc

Secondary structure

1 ............................... 143
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q3JRF0 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: F964A5CC23725C61

FASTA14316,187
        10         20         30         40         50         60 
MSGDRDDPRY PYPKDDAELR RRLTPMQYEV TQHAATEPPF TGEYTDTEDA GIYHCVVCGT 

        70         80         90        100        110        120 
ALFESGAKYH SGCGWPSYFK PIDGEVIDEK MDYTHGMTRV EVRCNQCGAH LGHVFEDGPR 

       130        140 
DKTGLRYCIN SAALNFEAKP ERK

« Hide

References

« Hide 'large scale' references
[1]Woods D.E., Nierman W.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1710b.
[2]"Methionine-R-sulfoxide reductase from Burkholderia pseudomallei."
Seattle structural genomics center for infectious disease (SSGCID)
Submitted (MAR-2008) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) IN COMPLEX WITH ZINC IONS.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000124 Genomic DNA. Translation: ABA49928.1.
RefSeqYP_333853.1. NC_007434.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3CEZX-ray2.10A/B1-143[»]
3CXKX-ray1.70A/B1-143[»]
ProteinModelPortalQ3JRF0.
SMRQ3JRF0. Positions 10-140.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3JRF0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3690705.
GenomeReviewsGene locus BURPS1710b_2458 in contig CP000124_GR.
KEGGbpm:BURPS1710b_2458.
PATRIC19237392. VBIBurPse115837_2569.
TIGRBURPS1710b_2458.

Phylogenomic databases

eggNOGCOG0229.
HOGENOMHBG715255.
OMAFTDGPVD.
PhylomeDBQ3JRF0.
ProtClustDBCLSK930638.

Family and domain databases

HAMAPMF_01400. MsrB.
[Tree]
InterProIPR002579. Methionine_sulphoxide_MsrB.
IPR011057. Mss4-like.
[Graphical view]
Gene3DG3DSA:2.170.150.20. MsrB. 1 hit.
KOK07305.
PfamPF01641. SelR. 1 hit.
[Graphical view]
SUPFAMSSF51316. Mss4_like. 1 hit.
TIGRFAMsTIGR00357. TIGR00357. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMSRB_BURP1
AccessionPrimary (citable) accession number: Q3JRF0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: November 8, 2005
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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