Q3JR24 (Q3JR24_BURP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163

Gene names

Name:	def EMBL ABA47944.1
Synonyms:	def2 HAMAP MF_00163
Ordered Locus Names:	BURPS1710b_2587

Organism

Burkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP] EMBL ABA47944.1

Taxonomic identifier

320372 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. HAMAP MF_00163

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00163 SAAS SAAS000181
Ligand	Iron HAMAP MF_00163 Metal-binding HAMAP MF_00163 SAAS SAAS000181
Molecular function	Hydrolase SAAS SAAS000181 HAMAP MF_00163 EMBL ABA47944.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	142	1	By similarity HAMAP MF_00163
	Metal binding	99	1	Iron By similarity HAMAP MF_00163
	Metal binding	141	1	Iron By similarity HAMAP MF_00163
	Metal binding	145	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	Q3JR24 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 7FAC1DBE77F1D60F	FASTA	177	19,697
	10 20 30 40 50 60 MIREILKMGD PRLLEVARPV EAFNTPELHA LVADMFETMH HANGAGLAAP QIGVGLQVII 70 80 90 100 110 120 FGFGSSERYP EAPPVPETVL VNPSIEYLPP DLEEGWEGCL SVPGLRGVVS RYRRVRYSGF 130 140 150 160 170 DQYGAKLERI AEGFHARVVQ HEYDHLIGKL YPMRITDFSK FGFADVLFPG LDAQADD

References

[1]	Woods D.E., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 1710b EMBL ABA47944.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000124 Genomic DNA. Translation: ABA47944.1.
RefSeq	YP_333979.1. NC_007434.1.
3D structure databases
ProteinModelPortal	Q3JR24.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3JR24.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3690263.
GenomeReviews	Gene locus BURPS1710b_2587 in contig CP000124_GR.
KEGG	bpm:BURPS1710b_2587.
PATRIC	19237686. VBIBurPse115837_2713.
TIGR	BURPS1710b_2587.
Phylogenomic databases
eggNOG	COG0242.
HOGENOM	HBG665227.
OMA	PRFKHIC.
PhylomeDB	Q3JR24.
ProtClustDB	PRK12846.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3JR24_BURP1

Accession

Primary (citable) accession number: Q3JR24

Entry history

Integrated into UniProtKB/TrEMBL:	November 8, 2005
Last sequence update:	November 8, 2005
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)