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Reviewed, UniProtKB/Swiss-Prot Q3JQC7 (ASTB_BURP1)

Last modified June 16, 2009. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    N-succinylarginine dihydrolase
    EC=3.5.3.23
Gene names
Name: astB
Ordered Locus Names: BURPS1710b_2842
OrganismBurkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP]
Taxonomic identifier320372 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

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Protein attributes

Sequence length446 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO2 By similarity.

Catalytic activity

N(2)-succinyl-L-arginine + 2 H2O = N(2)-succinyl-L-ornithine + 2 NH3 + CO2. HAMAP MF_01172

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5. HAMAP MF_01172

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the succinylarginine dihydrolase family.

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Ontologies

Keywords
   Biological processArginine metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine catabolic process to glutamate

Inferred from electronic annotation. Source: HAMAP

   Molecular functionN-succinylarginine dihydrolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 446446N-succinylarginine dihydrolase HAMAP MF_01172
PRO_0000262341

Regions

Region19 – 2810Substrate binding By similarity
Region137 – 1382Substrate binding By similarity

Sites

Active site1741 By similarity
Active site2491 By similarity
Active site3701Nucleophile By similarity
Binding site1101Substrate By similarity
Binding site2131Substrate By similarity
Binding site2511Substrate By similarity
Binding site3641Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q3JQC7-1 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 934449B79BB55B2F

FASTA44648,138
        10         20         30         40         50         60 
MNAKEANFDG LVGPTHNYAG LSFGNVASLS NEKSDANPKA AAKQGLRKMK QLADLGFAQG 

        70         80         90        100        110        120 
VLPPQERPSL RLLRELGFSG KDADVIAKAA RQAPELLAAA SSASAMWTAN AATVSPSADT 

       130        140        150        160        170        180 
SDARVHFTPA NLCSKLHRAI EHESTRRTLA AIFADEARFA VHDALPGTPA LGDEGAANHT 

       190        200        210        220        230        240 
RFCAEYGAPG VEFFVYGRAE YRRGPEPTRF PARQTFEASR AVAHRHGLRE EATIYAQQRP 

       250        260        270        280        290        300 
DVIDAGVFHN DVIAVGNRDT LFCHEHAFVD RQAVYDALAA SLGALGAQLN VIEVPDRAVS 

       310        320        330        340        350        360 
VADAVGSYLF NSQLLAREDG TQMLVVPQEC RENANVAAYL DALVAGNGPI RDVRVFDLRE 

       370        380        390        400        410        420 
SMKNGGGPAC LRLRVVLNDA ERAAVKPNVW IGDALFASLD AWIDKHYRDR LSPVDLADPA 

       430        440 
LLDESRTALD ELTQILGLGS LYDFQR

« Hide

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References

[1]Woods D.E., Nierman W.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000124 Genomic DNA. Translation: ABA49014.1.
RefSeqYP_334226.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3691235.
GenomeReviewsGene locus BURPS1710b_2842 in contig CP000124_GR.
KEGGbpm:BURPS1710b_2842.
TIGRBURPS1710b_2842.

Phylogenomic databases

HOGENOMQ3JQC7.
OMAQ3JQC7. HFAHHPA.

Enzyme and pathway databases

BioCycBPSE320372:BURPS1710B_A3087-MON.

Family and domain databases

HAMAPMF_01172.
[Tree]
InterProIPR007079. SuccinylArg_d-Hdrlase_AstB.
[Graphical view]
Gene3DG3DSA:3.75.10.20. SuccinylArg_di_hydro. 1 hit.
PfamPF04996. AstB. 1 hit.
[Graphical view]
TIGRFAMsTIGR03241. arg_catab_astB. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameASTB_BURP1
AccessionPrimary (citable) accession number: Q3JQC7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 8, 2005
Last modified: June 16, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents