Reviewed,
UniProtKB/Swiss-Prot Q3JQC6 (ASTD_BURP1)
Last modified
June 16, 2009.
Version 30.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: N-succinylglutamate 5-semialdehyde dehydrogenase EC=1.2.1.71 Alternative name(s): Succinylglutamic semialdehyde dehydrogenase Short name=SGSD | ||||
| Gene names |
| ||||
| Organism | Burkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 320372 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group |
Protein attributes
| Sequence length | 487 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. |
| Catalytic activity | N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174 |
| Pathway | Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174 |
| Sequence similarities | Belongs to the aldehyde dehydrogenase family. AstD subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Arginine metabolism |
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine catabolic process to glutamate Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | succinylglutamate-semialdehyde dehydrogenase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 487 | 487 | N-succinylglutamate 5-semialdehyde dehydrogenase HAMAP MF_01174 | PRO_0000262390 | |||||
Regions | |||||||||
| Nucleotide binding | 221 – 226 | 6 | NAD By similarity | ||||||
Sites | |||||||||
| Active site | 244 | 1 | By similarity | ||||||
| Active site | 278 | 1 | By similarity | ||||||
Sequences
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References
| [1] | Woods D.E., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000124 Genomic DNA. Translation: ABA50055.1. | |
| RefSeq | YP_334227.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3688653. |
| GenomeReviews | Gene locus BURPS1710b_2843 in contig CP000124_GR. |
| KEGG | bpm:BURPS1710b_2843. |
| TIGR | BURPS1710b_2843. |
Phylogenomic databases | |
| HOGENOM | Q3JQC6. |
| OMA | Q3JQC6. EMTQPQA. |
Enzyme and pathway databases | |
| BioCyc | BPSE320372:BURPS1710B_A3088-MON. |
Family and domain databases | |
| HAMAP | MF_01174. [Tree] |
| InterPro | IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH. IPR017649. SuccinylGlu_semiald_DH_AstD. [Graphical view] |
| Gene3D | G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit. |
| PANTHER | PTHR11699. Aldehyde_dehyd. 1 hit. |
| Pfam | PF00171. Aldedh. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR03240. arg_catab_astD. 1 hit. |
| PROSITE | PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ASTD_BURP1 | ||||||||
| Accession | Primary (citable) accession number: Q3JQC6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


