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Q3JPL2

- TRMB_BURP1

UniProt

Q3JPL2 - TRMB_BURP1

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, BURPS1710b_3119
Organism
Burkholderia pseudomallei (strain 1710b)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei95 – 951S-adenosyl-L-methionine By similarity
Binding sitei120 – 1201S-adenosyl-L-methionine By similarity
Binding sitei147 – 1471S-adenosyl-L-methionine By similarity
Active sitei170 – 1701 By similarity
Binding sitei170 – 1701S-adenosyl-L-methionine By similarity
Binding sitei174 – 1741Substrate By similarity
Binding sitei206 – 2061Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciBPSE320372:GBYB-3119-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:BURPS1710b_3119
OrganismiBurkholderia pseudomallei (strain 1710b)
Taxonomic identifieri320372 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
ProteomesiUP000002700: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 265265tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
PRO_0000229157Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi320372.BURPS1710b_3119.

Structurei

3D structure databases

ProteinModelPortaliQ3JPL2.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni241 – 2444Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000073968.
KOiK03439.
OMAiHSTLEMA.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3JPL2-1 [UniParc]FASTAAdd to Basket

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MIHDDDPNAP GAPHDDDATA APASATRAAP AAGDDDDANP LHLRRIRSFV    50
TRAGRVSTGQ RRAIDELGPR FVIPYGSAQP DWDAIFGRRA PRVLEIGFGM 100
GASTAEIAAL RPGDDFIGVE VHEPGVGALL KLIGEQQLSN IRIIQHDAVE 150
VLAQMIAPDS LDGVHIFFPD PWHKARHHKR RLIQPPFVAQ LAAHLKPGAY 200
LHCATDWQNY AEQMLEVLSA DPSLENTAQD YAPRPGYRPV TKFERRGLRL 250
GHGVWDLVFR KKHAG 265
Length:265
Mass (Da):29,102
Last modified:November 8, 2005 - v1
Checksum:iD19E15399EE03B40
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000124 Genomic DNA. Translation: ABA49298.1.
RefSeqiYP_334491.1. NC_007434.1.

Genome annotation databases

EnsemblBacteriaiABA49298; ABA49298; BURPS1710b_3119.
GeneIDi3688754.
KEGGibpm:BURPS1710b_3119.
PATRICi19238802. VBIBurPse115837_3252.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000124 Genomic DNA. Translation: ABA49298.1 .
RefSeqi YP_334491.1. NC_007434.1.

3D structure databases

ProteinModelPortali Q3JPL2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 320372.BURPS1710b_3119.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA49298 ; ABA49298 ; BURPS1710b_3119 .
GeneIDi 3688754.
KEGGi bpm:BURPS1710b_3119.
PATRICi 19238802. VBIBurPse115837_3252.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000073968.
KOi K03439.
OMAi HSTLEMA.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci BPSE320372:GBYB-3119-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Woods D.E., Nierman W.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1710b.

Entry informationi

Entry nameiTRMB_BURP1
AccessioniPrimary (citable) accession number: Q3JPL2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: November 8, 2005
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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