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Q3JP21

- PUR5_BURP1

UniProt

Q3JP21 - PUR5_BURP1

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Burkholderia pseudomallei (strain 1710b)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBPSE320372:GBYB-3311-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:BURPS1710b_3311
OrganismiBurkholderia pseudomallei (strain 1710b)
Taxonomic identifieri320372 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
ProteomesiUP000002700: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000258341Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi320372.BURPS1710b_3311.

Structurei

3D structure databases

ProteinModelPortaliQ3JP21.
SMRiQ3JP21. Positions 13-350.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiVIGKIEH.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3JP21-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNPPKSAPDA QGLSYRDAGV DIDAGDALVD KIKPFAKKTL RDGVLGGIGG
60 70 80 90 100
FGALFEVPKK YREPVLVSGT DGVGTKLKLA FHLNKHDTVG QDLVAMSVND
110 120 130 140 150
ILVQGAEPLF FLDYFACGKL DVETAATVVK GIATGCELAG CALIGGETAE
160 170 180 190 200
MPGMYPDGEY DLAGFAVGAV EKSKIIDGST IAEGDVVLGL ASSGIHSNGF
210 220 230 240 250
SLVRKIIERA NPDLSADFHG RSLADALMAP TRIYVKPLLA LMEKIAVKGM
260 270 280 290 300
AHITGGGLVE NIPRVLRDGL TAELDQHAWP LPPLFQWLRQ HGGVADAEMH
310 320 330 340 350
RVFNCGIGMA VIVSAADADD ALRQLADAGE QVWKIGTVRA SREGEAQTVV

V
Length:351
Mass (Da):36,941
Last modified:November 8, 2005 - v1
Checksum:iBB27286317BCFCF9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000124 Genomic DNA. Translation: ABA49845.1.
RefSeqiYP_334682.1. NC_007434.1.

Genome annotation databases

EnsemblBacteriaiABA49845; ABA49845; BURPS1710b_3311.
GeneIDi3689806.
KEGGibpm:BURPS1710b_3311.
PATRICi19239198. VBIBurPse115837_3449.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000124 Genomic DNA. Translation: ABA49845.1 .
RefSeqi YP_334682.1. NC_007434.1.

3D structure databases

ProteinModelPortali Q3JP21.
SMRi Q3JP21. Positions 13-350.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 320372.BURPS1710b_3311.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA49845 ; ABA49845 ; BURPS1710b_3311 .
GeneIDi 3689806.
KEGGi bpm:BURPS1710b_3311.
PATRICi 19239198. VBIBurPse115837_3449.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi VIGKIEH.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci BPSE320372:GBYB-3311-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Woods D.E., Nierman W.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1710b.

Entry informationi

Entry nameiPUR5_BURP1
AccessioniPrimary (citable) accession number: Q3JP21
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 8, 2005
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3