Q3JNI9 (Q3JNI9_BURP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE HAMAP MF_00222
Ordered Locus Names:	BURPS1710b_3493

Organism

Burkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP] EMBL ABA49406.1

Taxonomic identifier

320372 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00222
Ligand	NADP HAMAP MF_00222
Molecular function	Oxidoreductase HAMAP MF_00222 EMBL ABA49406.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	137 – 141	5	NADP By similarity HAMAP MF_00222
Sites
	Active site	76	1	Proton acceptor By similarity HAMAP MF_00222

Sequences

	Sequence		Length	Mass (Da)
	Q3JNI9 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 1FC4AA40A1940D77	FASTA	292	30,004
	10 20 30 40 50 60 MSTAVESAAR ARDRYAVIGN PIAHSKSPFI HSRFAEQTGE AIEYTHLLAP LDGFSATVRA 70 80 90 100 110 120 FIAQGGRGVN VTVPFKLEAY ALADALSPRA AAAGAVNTLR FDADGVFGDN TDGVGLVRDI 130 140 150 160 170 180 EVNLGVSLTG ARILLLGAGG AARGVVLPML ERGPASLTIV NRTASKAEEL VGQFTQAAHD 190 200 210 220 230 240 AGCVLAGGGP ERIAREPYDV IVNATAGSLD AALPECDAAA FGPATLAYDM MYGARPTVFM 250 260 270 280 290 EHAAALGART ADGLGMLVEQ AAESFHVWRG VRPDSAPVLA ALRAALAASA AH

References

[1]	Woods D.E., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 1710b EMBL ABA49406.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000124 Genomic DNA. Translation: ABA49406.1.
RefSeq	YP_334864.1. NC_007434.1.
3D structure databases
ProteinModelPortal	Q3JNI9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3JNI9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3690651.
GenomeReviews	Gene locus BURPS1710b_3493 in contig CP000124_GR.
KEGG	bpm:BURPS1710b_3493.
PATRIC	19239572. VBIBurPse115837_3636.
TIGR	BURPS1710b_3493.
Phylogenomic databases
eggNOG	COG0169.
HOGENOM	HBG553408.
OMA	VVFGNPI.
PhylomeDB	Q3JNI9.
ProtClustDB	PRK00258.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3JNI9_BURP1

Accession

Primary (citable) accession number: Q3JNI9

Entry history

Integrated into UniProtKB/TrEMBL:	November 8, 2005
Last sequence update:	November 8, 2005
Last modified:	December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)