Reviewed,
UniProtKB/Swiss-Prot Q3JN04 (HIS2_BURP1)
Last modified
February 9, 2010.
Version 26.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Phosphoribosyl-ATP pyrophosphatase Short name=PRA-PH EC=3.6.1.31 | ||||
| Gene names |
| ||||
| Organism | Burkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 320372 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group |
Protein attributes
| Sequence length | 122 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | 1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)-AMP + diphosphate. HAMAP MF_01020 |
| Pathway | Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9. HAMAP MF_01020 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_01020. |
| Sequence similarities | Belongs to the PRA-PH family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Histidine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosyl-ATP diphosphatase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 122 | 122 | Phosphoribosyl-ATP pyrophosphatase HAMAP MF_01020 | PRO_0000230172 | |||
Sequences
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References
| [1] | Woods D.E., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000124 Genomic DNA. Translation: ABA49664.1. |
| RefSeq | YP_335049.1. |
3D structure databases | |
| SMR | Q3JN04. Positions 8-102. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q3JN04. |
Genome annotation databases | |
| GeneID | 3689524. |
| GenomeReviews | Gene locus BURPS1710b_3685 in contig CP000124_GR. |
| KEGG | bpm:BURPS1710b_3685. |
| TIGR | BURPS1710b_3685. |
Phylogenomic databases | |
| eggNOG | COG0140. |
| HOGENOM | HBG646527. |
| OMA | ETVMAAK. |
Enzyme and pathway databases | |
| BioCyc | BPSE320372:BURPS1710B_A3983-MONOMER. |
Family and domain databases | |
| HAMAP | MF_01020. HisE. [Tree] |
| InterPro | IPR008179. PRib-ATP_pyrophosphohydrolase. IPR021130. PRib-ATP_pyroPHydrolase-like. [Graphical view] |
| Pfam | PF01503. PRA-PH. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR03188. histidine_hisI. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | HIS2_BURP1 | ||||||||
| Accession | Primary (citable) accession number: Q3JN04 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


