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Q3JMW1 (AROB_BURP1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:BURPS1710b_3728
OrganismBurkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP]
Taxonomic identifier320372 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3593593-dehydroquinate synthase HAMAP MF_00110
PRO_0000231075

Sequences

Sequence LengthMass (Da)Tools
Q3JMW1 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: CFD37136057BD086

FASTA35937,896
        10         20         30         40         50         60 
MITVNVDLGE RAYPIHIGAD LIGRTELFAP HIAGASVTIV TNTTVEPLYG DTLRAALAPL 

        70         80         90        100        110        120 
GKRVSTVVLP DGEAYKNWET LNLIFDGLLE QHADRKTTLI ALGGGVIGDM TGFAAACYMR 

       130        140        150        160        170        180 
GVPFIQVPTT LLSQVDSSVG GKTGINHPLG KNMIGAFYQP QAVIADIGAL STLPDRELAA 

       190        200        210        220        230        240 
GVAEIVKTGA IADAAFFDWI EANVGALTRR DPDALAHAVK RSCEIKAGVV AADEREGGLR 

       250        260        270        280        290        300 
AILNFGHTFG HAIEAGLGYG EWLHGEAVGC GMVMAADLSV RTGHLDEASR ARLCRVVEAA 

       310        320        330        340        350 
HLPTRAPDLG DARYVELMRV DKKAEAGAIK FILLKRFGET IITPAPDDAV LATLAATTR

« Hide

References

[1]Woods D.E., Nierman W.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1710b.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000124 Genomic DNA. Translation: ABA48638.1.
RefSeqYP_335092.1. NC_007434.1.

3D structure databases

ProteinModelPortalQ3JMW1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3JMW1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3688943.
GenomeReviewsGene locus BURPS1710b_3728 in contig CP000124_GR.
KEGGbpm:BURPS1710b_3728.
PATRIC19240064. VBIBurPse115837_3875.
TIGRBURPS1710b_3728.

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ3JMW1.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycBPSE320372:BURPS1710B_A4022-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_BURP1
AccessionPrimary (citable) accession number: Q3JMW1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: November 8, 2005
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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