Q3JMW0 (AROK_BURP1) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 40.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Shikimate kinase Short name=SK EC=2.7.1.71 | ||||
| Gene names |
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| Organism | Burkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 320372 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group |
Protein attributes
| Sequence length | 184 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate By similarity. HAMAP MF_00109 |
| Catalytic activity | ATP + shikimate = ADP + shikimate 3-phosphate. HAMAP MF_00109 |
| Cofactor | Binds 1 magnesium ion per subunit By similarity. HAMAP MF_00109 |
| Pathway | Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7. HAMAP MF_00109 |
| Subunit structure | Monomer By similarity. HAMAP MF_00109 |
| Subcellular location | Cytoplasm Probable HAMAP MF_00109. |
| Sequence similarities | Belongs to the shikimate kinase family. |
| Sequence caution | The sequence ABA49770.1 differs from that shown. Reason: Erroneous initiation. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Magnesium Metal-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW shikimate kinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 184 | 184 | Shikimate kinase HAMAP MF_00109 | PRO_0000237859 | |||||
Regions | |||||||||
| Nucleotide binding | 17 – 22 | 6 | ATP By similarity | ||||||
Sites | |||||||||
| Metal binding | 21 | 1 | Magnesium By similarity | ||||||
| Binding site | 39 | 1 | Substrate By similarity | ||||||
| Binding site | 63 | 1 | Substrate By similarity | ||||||
| Binding site | 85 | 1 | Substrate; via amide nitrogen By similarity | ||||||
| Binding site | 123 | 1 | ATP By similarity | ||||||
| Binding site | 142 | 1 | Substrate By similarity | ||||||
Sequences
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References
| [1] | Woods D.E., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1710b. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000124 Genomic DNA. Translation: ABA49770.1. Different initiation. |
| RefSeq | YP_335093.2. NC_007434.1. |
3D structure databases | |
| ProteinModelPortal | Q3JMW0. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q3JMW0. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 3691445. |
| GenomeReviews | Gene locus BURPS1710b_3729 in contig CP000124_GR. |
| KEGG | bpm:BURPS1710b_3729. |
| PATRIC | 19240066. VBIBurPse115837_3876. |
| TIGR | BURPS1710b_3729. |
Phylogenomic databases | |
| eggNOG | COG0703. |
| HOGENOM | HBG335815. |
| PhylomeDB | Q3JMW0. |
| ProtClustDB | PRK00131. |
Family and domain databases | |
| HAMAP | MF_00109. Shikimate_kinase. [Tree] |
| InterPro | IPR000623. Shikimate_kinase. IPR023000. Shikimate_kinase_CS. [Graphical view] |
| KO | K00891. |
| Pfam | PF01202. SKI. 1 hit. [Graphical view] |
| PRINTS | PR01100. SHIKIMTKNASE. |
| PROSITE | PS01128. SHIKIMATE_KINASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AROK_BURP1 | ||||||||
| Accession | Primary (citable) accession number: Q3JMW0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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