Reviewed, UniProtKB/Swiss-Prot Q3JJ81 (UBIC1_BURP1)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase 1
      Short name=CL 1
      Short name=CPL 1
    EC=4.1.3.40

Gene names

Name:	ubiC1
Ordered Locus Names:	BURPS1710b_A1215

Organism

Burkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP]

Taxonomic identifier

320372 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	184 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity HAMAP MF_01632.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 184	184	Probable chorismate--pyruvate lyase 1 HAMAP MF_01632		PRO_0000240539
Sites
	Binding site	70	1	Substrate By similarity
	Binding site	108	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3JJ81-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: E99ABAFA51E3D1D5	FASTA	184	19,954
	10 20 30 40 50 60 MNTSSGWSRQ PPASLSELEI HWLFAPGSLT ERLSALGEYS LEPVDQRHAA ACAADASLLG 70 80 90 100 110 120 VEPDSPIWVR EVVMRLDAQP CVTARSIASA HALETQWKPL TGYGSLPLGH ILYDDPAIVR 130 140 150 160 170 180 APFECALLMP DDPLDAISRR YARAAAPPRA RRSAFVRNGA TLVVSECFLP QFWSGFAQAR LAGA

References

[1]	Woods D.E., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000125 Genomic DNA. Translation: ABA51190.1.
RefSeq	YP_336372.1.
3D structure databases
SMR	Q3JJ81. Positions 5-172.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3JJ81.
Genome annotation databases
GeneID	3693109.
GenomeReviews	Gene locus BURPS1710b_A1215 in contig CP000125_GR.
KEGG	bpm:BURPS1710b_A1215.
TIGR	BURPS1710b_A1215.
Phylogenomic databases
eggNOG	COG3161.
HOGENOM	HBG644467.
OMA	LIARCEC.
Enzyme and pathway databases
BioCyc	BPSE320372:BURPS1710B_B1436-MONOMER.
Family and domain databases
HAMAP	MF_01632. UbiC. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC1_BURP1

Accession

Primary (citable) accession number: Q3JJ81

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	November 8, 2005
Last modified:	January 19, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)