Reviewed, UniProtKB/Swiss-Prot Q3JJ76 (SDHD_BURP1)

Names and origin

Protein names

Recommended name:
    Probable D-serine dehydratase
    EC=4.3.1.18
Alternative name(s):
    D-serine deaminase
      Short name=DSD

Gene names

Name:	dsdA
Ordered Locus Names:	BURPS1710b_A1220

Organism

Burkholderia pseudomallei (strain 1710b) [Complete proteome] [HAMAP]

Taxonomic identifier

320372 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	445 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-serine = pyruvate + NH3. HAMAP MF_01030
Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the serine/threonine dehydratase family. DsdA subfamily.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	D-amino acid metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	D-serine ammonia-lyase activity Inferred from electronic annotation. Source: EC hydro-lyase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 445	445	Probable D-serine dehydratase HAMAP MF_01030		PRO_0000291720
Amino acid modifications
	Modified residue	111	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3JJ76-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: F4E22B08A8B6EAD6	FASTA	445	46,292
	10 20 30 40 50 60 MPVGRSLSLD PNLLAQLQSH SPTLWLNPHQ GMPLPDFAPT AADLADADAR LRRCAGLLAE 70 80 90 100 110 120 LFAELRPSGG LIASPLQPAE PLKRAARAGH AQAGAWYVKR DDALPVAGSI KARGGFHEVL 130 140 150 160 170 180 ALAESIAERH GLAGADTDRR ALASGAARAR FARHTVMVGS TGNLGLSIGM LASALGFRTV 190 200 210 220 230 240 AHMSADAKAW KKARLRTRGV EVVEHAGDYA KAVDAGRRQA AGMPCCHFVD DEGSRMLFLG 250 260 270 280 290 300 YATAAAELAA QLAQAGRPVD ARHPLFVHLP CGVGGAPGGI VYGLKALYGE HVHAFVAEPT 310 320 330 340 350 360 ASPCVLVQLA GDAAHPRSVY DIGLDNRTEA DGLAVAQASP LAAALLRAQA AGAFTVDDRQ 370 380 390 400 410 420 LFAHLLDARE RLGIDLEPSA AAAFGGPAWI AGSDAGRAYL RGRGIDPDAA THVIWATGGS 430 440 LVPAQEHRRF QAHARAQRQV GGAGA

References

[1]	Woods D.E., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000125 Genomic DNA. Translation: ABA52188.1.
RefSeq	YP_336377.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3693364.
GenomeReviews	Gene locus BURPS1710b_A1220 in contig CP000125_GR.
KEGG	bpm:BURPS1710b_A1220.
TIGR	BURPS1710b_A1220.
Phylogenomic databases
HOGENOM	Q3JJ76.
OMA	Q3JJ76. DHPLFVY.
Enzyme and pathway databases
BioCyc	BPSE320372:BURPS1710B_B1440-MON.
Family and domain databases
HAMAP	MF_01030. [Tree]
InterPro	IPR011780. D_Ser_am_lyase. IPR001926. PyrdxlP-dep_enz_bsu. IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS. [Graphical view]
PANTHER	PTHR10314:SF9. D_Ser_am_lyase. 1 hit.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
TIGRFAMs	TIGR02035. D_Ser_am_lyase. 1 hit.
PROSITE	PS00165. DEHYDRATASE_SER_THR. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SDHD_BURP1

Accession

Primary (citable) accession number: Q3JJ76

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	November 8, 2005
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)