ID   GLGA1_NITOC             Reviewed;         487 AA.
AC   Q3JEW3;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   RecName: Full=Glycogen synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase 1 {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA1 {ECO:0000255|HAMAP-Rule:MF_00484};
GN   OrderedLocusNames=Noc_0100;
OS   Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB
OS   11848 / C-107).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC   Nitrosococcus.
OX   NCBI_TaxID=323261;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107;
RX   PubMed=16957257; DOI=10.1128/aem.00463-06;
RA   Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J.,
RA   Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T.,
RA   Vergez L.M., Ward B.B.;
RT   "Complete genome sequence of the marine, chemolithoautotrophic, ammonia-
RT   oxidizing bacterium Nitrosococcus oceani ATCC 19707.";
RL   Appl. Environ. Microbiol. 72:6299-6315(2006).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; CP000127; ABA56633.1; -; Genomic_DNA.
DR   RefSeq; WP_011330231.1; NC_007484.1.
DR   AlphaFoldDB; Q3JEW3; -.
DR   SMR; Q3JEW3; -.
DR   STRING; 323261.Noc_0100; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   KEGG; noc:Noc_0100; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_3_6; -.
DR   InParanoid; Q3JEW3; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000006838; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd03791; GT5_Glycogen_synthase_DULL1-like; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   NCBIfam; TIGR02095; glgA; 1.
DR   PANTHER; PTHR46083; -; 1.
DR   PANTHER; PTHR46083:SF1; GLYCOGEN SYNTHASE 2-RELATED; 1.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..487
FT                   /note="Glycogen synthase 1"
FT                   /id="PRO_0000230248"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   487 AA;  56489 MW;  7C21E978FBF3C94A CRC64;
     MYIVMITPEC APIAKVGGLG DVVQGLSNEL SIRGNTVELI LPKYDCMRYE RIWGLEKTHN
     NLWVPYHDQW IPCDVYFGFA EGLKCFFIEP HNGFFQRGTY YGQPDDPQRF AFFCKAALEF
     MLRSNKYPEI IHCHDWQTGL VPVLLFEQYK YLGMTHPRVC YTLHNMRHQG VTGGHILQQV
     GLDPAAYMTP ERLLDHTYPH GVNLMKGGIV FSNFITTVSP RYLDEIRYTD QGYGLQHTLH
     EHSQKLGGIL NGVDYKVWNP DIDPYIAARY NLKTLDKKYE NKTALRHRLW LRDEYKPIVG
     VISRLDPQKG VELIRHALFY CLANGCQFVL LGASASNSIN ADFWYLKQYL NDDPDCHLEI
     GYDEDLAHQI YAGADMLIVP SIYEPCGLTQ MIAMKYGTVP IVRHVGGLAD TVFDANYAHK
     PYHERNGFVF HDFNHEGIEA ALHRAIGLWY EYPQYFRELM ENGMRYDFSW NHPGQHYLNI
     YHHIQEI
//