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Protein

Glutamate-ammonia-ligase adenylyltransferase

Gene

glnE

Organism
Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Adenylation and deadenylation of glutamate--ammonia ligase.UniRule annotation

Catalytic activityi

ATP + [glutamine synthetase]-L-tyrosine = diphosphate + [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Magnesium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-ammonia-ligase adenylyltransferaseUniRule annotation (EC:2.7.7.42UniRule annotation)
Alternative name(s):
Glutamine-synthetase adenylyltransferase
Short name:
ATaseUniRule annotation
[Glutamate--ammonia-ligase] adenylyltransferaseUniRule annotation
Gene namesi
Name:glnEUniRule annotation
Ordered Locus Names:Noc_0135
OrganismiNitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)
Taxonomic identifieri323261 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeNitrosococcus
Proteomesi
  • UP000006838 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001485441 – 969Glutamate-ammonia-ligase adenylyltransferaseAdd BLAST969

Interactioni

Protein-protein interaction databases

STRINGi323261.Noc_0135.

Structurei

3D structure databases

ProteinModelPortaliQ3JES8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni107 – 318GlnE 1Add BLAST212
Regioni626 – 850GlnE 2Add BLAST225

Sequence similaritiesi

Belongs to the GlnE family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiTWERIAW.
OrthoDBiPOG091H0675.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3JES8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNWQANIHKL PALLQGRLKN DLARFQEALE QKNLDTVFKA KTLKTLCLVW
60 70 80 90 100
GASEFVATNC IRWPSLLLDL QGSGNLFRAY EPNHYVKSLA QQLTNISTET
110 120 130 140 150
ELMVVLRRFR QREMVRIVWR DLAGWASLDE VFRELSQLAE ACLNSALACL
160 170 180 190 200
HYWQSQALGT PYGSISGKPQ SMVVLGMGKL GARELNLSSD IDLIFAYPES
210 220 230 240 250
GETRGAQRTL NNEEYFIRLA RRLIRVLDER TEEGFVFRVD MRLRPDGDSG
260 270 280 290 300
PLVASFNAME NYYQNQGRDW ERYAMIKARV VAGDCQAGTR LMAMLRPFSY
310 320 330 340 350
RRYLDFGAIE SLRSMKAMIA QELRRQGIKA NIKLGPGGIR EVEFIGQSFQ
360 370 380 390 400
LIRGGRESAL QERGILRVLT LLAERDHLPY YAKEELCAAY VFLRRVEHRL
410 420 430 440 450
QAYRDEQTHD LPTSTEGRVR LAFAMGYRDW EAFASALEEH RRRVQEHFEQ
460 470 480 490 500
LFAAPHMDIT DQMAQEKRLA EVWLGGELRE ASLAVLSAAG YRAPEEAVQT
510 520 530 540 550
LMYLRQSYTV RALSAQARIR LDRLMPLLLG AVGRTEYPEQ CLQRVIILLE
560 570 580 590 600
TVAQRTAYLA LLAEYPMALS QLVKLCAASP LIARQLTRYP LLLDELLDPR
610 620 630 640 650
SLYQVLGYDS LAEDLKWSLE SIPGDDLEQQ MELLRHFCQR QTLRVAAADV
660 670 680 690 700
TGVLPLMKVG DHLTYLAEVI LKKALELSWR HLVHRHGRLQ SSTGEQPEES
710 720 730 740 750
GFAVIGYGKL GGYELGYGSD LDLVFLHNAK PGDPPSEGKK PLDPVVFYSR
760 770 780 790 800
LGQRLIHILQ TSTPSGKLYE VDTRLRPSGV SGLLVSGLDA YRGYQCMQAW
810 820 830 840 850
TWEHQALVRA RFVAGDARLG AAFTAMRQEI LGRQRDPIKL RDEVRHMRAK
860 870 880 890 900
MRNQLDRSQG GWFDLKQGRG GIADIEFIVQ YGVLAWAHAH PQLLEYPDNI
910 920 930 940 950
RILEGFAQAG LLASEESQLL ADAYRAYRAA ANRLNLQTHE ARVEEGQFRQ
960
ERIAVQQLWS ALLEDESAK
Length:969
Mass (Da):110,170
Last modified:November 8, 2005 - v1
Checksum:i2A9579DDA4A2DB73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000127 Genomic DNA. Translation: ABA56668.1.
RefSeqiWP_002813656.1. NC_007484.1.

Genome annotation databases

EnsemblBacteriaiABA56668; ABA56668; Noc_0135.
KEGGinoc:Noc_0135.
PATRICi22703928. VBINitOce57959_0211.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000127 Genomic DNA. Translation: ABA56668.1.
RefSeqiWP_002813656.1. NC_007484.1.

3D structure databases

ProteinModelPortaliQ3JES8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi323261.Noc_0135.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA56668; ABA56668; Noc_0135.
KEGGinoc:Noc_0135.
PATRICi22703928. VBINitOce57959_0211.

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiTWERIAW.
OrthoDBiPOG091H0675.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLNE_NITOC
AccessioniPrimary (citable) accession number: Q3JES8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: November 8, 2005
Last modified: November 2, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.