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Q3JCM6

- Q3JCM6_NITOC

UniProt

Q3JCM6 - Q3JCM6_NITOC

Protein

Probable glycine dehydrogenase [decarboxylating] subunit 1

Gene

gcvPA

Organism
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.UniRule annotationSAAS annotation

    Catalytic activityi

    Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotationSAAS annotation

    GO - Molecular functioni

    1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glycine catabolic process Source: InterPro
    2. nucleoside metabolic process Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationSAAS annotationImported

    Enzyme and pathway databases

    BioCyciNOCE323261:GCI3-917-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glycine dehydrogenase [decarboxylating] subunit 1UniRule annotation (EC:1.4.4.2UniRule annotation)
    Alternative name(s):
    Glycine cleavage system P-protein subunit 1UniRule annotation
    Glycine decarboxylase subunit 1UniRule annotation
    Glycine dehydrogenase (aminomethyl-transferring) subunit 1UniRule annotation
    Gene namesi
    Name:gcvPAUniRule annotation
    Ordered Locus Names:Noc_0908Imported
    OrganismiNitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)Imported
    Taxonomic identifieri323261 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeNitrosococcus
    ProteomesiUP000006838: Chromosome

    Interactioni

    Subunit structurei

    The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.UniRule annotationSAAS annotation

    Protein-protein interaction databases

    STRINGi323261.Noc_0908.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3JCM6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GcvP family. N-terminal subunit subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0403.
    HOGENOMiHOG000132025.
    KOiK00282.
    OMAiFFHEAVL.
    OrthoDBiEOG6XWV3B.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    HAMAPiMF_00712. GcvPA.
    InterProiIPR023010. GcvPA.
    IPR020580. GDC-P_N.
    IPR020581. GDC_P.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11773. PTHR11773. 1 hit.
    PfamiPF02347. GDC-P. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006815. GcvPA. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3JCM6-1 [UniParc]FASTAAdd to Basket

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    MPFIPHTDED IRAMLATAGV PDIETLFDEI PADLRTTDFD AVPPGLNEME    50
    VSRLLQERAA QNRPTVCFAG GGAYQHHIPA AVWEITSRGE YYSAYTPYQA 100
    EASQGTLQVI YEYQSMMTAL TGMEVSNASI YDGASALGEA VLMAVRLSRR 150
    GKSSCVLLPA TVHPAYRQVV ATLVGDQGIS LQEISYDFGS GVVEPETLES 200
    IQKDFAALVI PQPNYFGCLE EVDTLTNWAH ERGALVIGVV NPTSLALLKP 250
    PGEWGEAGAD IVCGEGQPLG IPLASGGPYF GFMACKQAHV RQLPGRIVGR 300
    TVDLESKPGY TLTLQAREQH IRRSKATSNI CTNQGLMVTA ATLYMALLGP 350
    QGLAQVATAC HANTMALVKR LTALPGVEQV FEKPFFHEAV LRFPVPASRV 400
    LSVLGQGGVL AGVKLEQAYP ELNDTLLVCA TELRNEEDIE FYVRELTAAL 450
    AG 452
    Length:452
    Mass (Da):48,712
    Last modified:November 8, 2005 - v1
    Checksum:i1A63F957578F4370
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000127 Genomic DNA. Translation: ABA57420.1.
    RefSeqiYP_342950.1. NC_007484.1.

    Genome annotation databases

    EnsemblBacteriaiABA57420; ABA57420; Noc_0908.
    GeneIDi3707293.
    KEGGinoc:Noc_0908.
    PATRICi22705686. VBINitOce57959_1082.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000127 Genomic DNA. Translation: ABA57420.1 .
    RefSeqi YP_342950.1. NC_007484.1.

    3D structure databases

    ProteinModelPortali Q3JCM6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 323261.Noc_0908.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABA57420 ; ABA57420 ; Noc_0908 .
    GeneIDi 3707293.
    KEGGi noc:Noc_0908.
    PATRICi 22705686. VBINitOce57959_1082.

    Phylogenomic databases

    eggNOGi COG0403.
    HOGENOMi HOG000132025.
    KOi K00282.
    OMAi FFHEAVL.
    OrthoDBi EOG6XWV3B.

    Enzyme and pathway databases

    BioCyci NOCE323261:GCI3-917-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    HAMAPi MF_00712. GcvPA.
    InterProi IPR023010. GcvPA.
    IPR020580. GDC-P_N.
    IPR020581. GDC_P.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11773. PTHR11773. 1 hit.
    Pfami PF02347. GDC-P. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006815. GcvPA. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the marine, chemolithoautotrophic, ammonia-oxidizing bacterium Nitrosococcus oceani ATCC 19707."
      Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J., Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T., Vergez L.M., Ward B.B.
      Appl. Environ. Microbiol. 72:6299-6315(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 19707 / NCIMB 11848Imported.

    Entry informationi

    Entry nameiQ3JCM6_NITOC
    AccessioniPrimary (citable) accession number: Q3JCM6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 8, 2005
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3