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Q3JCM6

- Q3JCM6_NITOC

UniProt

Q3JCM6 - Q3JCM6_NITOC

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Protein

Probable glycine dehydrogenase (decarboxylating) subunit 1

Gene

gcvPA

Organism
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.UniRule annotationSAAS annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotationSAAS annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine catabolic process Source: InterPro
  2. nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciNOCE323261:GCI3-917-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotation (EC:1.4.4.2UniRule annotation)
Alternative name(s):
Glycine cleavage system P-protein subunit 1UniRule annotation
Glycine decarboxylase subunit 1UniRule annotation
Glycine dehydrogenase (aminomethyl-transferring) subunit 1UniRule annotation
Gene namesi
Name:gcvPAUniRule annotation
Ordered Locus Names:Noc_0908Imported
OrganismiNitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)Imported
Taxonomic identifieri323261 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeNitrosococcus
ProteomesiUP000006838: Chromosome

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi323261.Noc_0908.

Structurei

3D structure databases

ProteinModelPortaliQ3JCM6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvP family. N-terminal subunit subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0403.
HOGENOMiHOG000132025.
KOiK00282.
OMAiFFHEAVL.
OrthoDBiEOG6XWV3B.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
HAMAPiMF_00712. GcvPA.
InterProiIPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 1 hit.
[Graphical view]
PIRSFiPIRSF006815. GcvPA. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3JCM6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPFIPHTDED IRAMLATAGV PDIETLFDEI PADLRTTDFD AVPPGLNEME
60 70 80 90 100
VSRLLQERAA QNRPTVCFAG GGAYQHHIPA AVWEITSRGE YYSAYTPYQA
110 120 130 140 150
EASQGTLQVI YEYQSMMTAL TGMEVSNASI YDGASALGEA VLMAVRLSRR
160 170 180 190 200
GKSSCVLLPA TVHPAYRQVV ATLVGDQGIS LQEISYDFGS GVVEPETLES
210 220 230 240 250
IQKDFAALVI PQPNYFGCLE EVDTLTNWAH ERGALVIGVV NPTSLALLKP
260 270 280 290 300
PGEWGEAGAD IVCGEGQPLG IPLASGGPYF GFMACKQAHV RQLPGRIVGR
310 320 330 340 350
TVDLESKPGY TLTLQAREQH IRRSKATSNI CTNQGLMVTA ATLYMALLGP
360 370 380 390 400
QGLAQVATAC HANTMALVKR LTALPGVEQV FEKPFFHEAV LRFPVPASRV
410 420 430 440 450
LSVLGQGGVL AGVKLEQAYP ELNDTLLVCA TELRNEEDIE FYVRELTAAL

AG
Length:452
Mass (Da):48,712
Last modified:November 8, 2005 - v1
Checksum:i1A63F957578F4370
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000127 Genomic DNA. Translation: ABA57420.1.
RefSeqiYP_342950.1. NC_007484.1.

Genome annotation databases

EnsemblBacteriaiABA57420; ABA57420; Noc_0908.
GeneIDi3707293.
KEGGinoc:Noc_0908.
PATRICi22705686. VBINitOce57959_1082.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000127 Genomic DNA. Translation: ABA57420.1 .
RefSeqi YP_342950.1. NC_007484.1.

3D structure databases

ProteinModelPortali Q3JCM6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 323261.Noc_0908.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA57420 ; ABA57420 ; Noc_0908 .
GeneIDi 3707293.
KEGGi noc:Noc_0908.
PATRICi 22705686. VBINitOce57959_1082.

Phylogenomic databases

eggNOGi COG0403.
HOGENOMi HOG000132025.
KOi K00282.
OMAi FFHEAVL.
OrthoDBi EOG6XWV3B.

Enzyme and pathway databases

BioCyci NOCE323261:GCI3-917-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
HAMAPi MF_00712. GcvPA.
InterProi IPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 1 hit.
[Graphical view ]
PIRSFi PIRSF006815. GcvPA. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the marine, chemolithoautotrophic, ammonia-oxidizing bacterium Nitrosococcus oceani ATCC 19707."
    Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J., Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T., Vergez L.M., Ward B.B.
    Appl. Environ. Microbiol. 72:6299-6315(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19707 / NCIMB 11848Imported.

Entry informationi

Entry nameiQ3JCM6_NITOC
AccessioniPrimary (citable) accession number: Q3JCM6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: November 26, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3