Q3JCM6 (Q3JCM6_NITOC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable glycine dehydrogenase [decarboxylating] subunit 1 HAMAP-Rule MF_00712
EC=1.4.4.2 HAMAP-Rule MF_00712

Alternative name(s):
Glycine cleavage system P-protein subunit 1 HAMAP-Rule MF_00712
Glycine decarboxylase subunit 1 HAMAP-Rule MF_00712

Gene names

Name:	gcvPA HAMAP-Rule MF_00712
Ordered Locus Names:	Noc_0908

Organism

Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) [Complete proteome] [HAMAP] EMBL ABA57420.1

Taxonomic identifier

323261 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Chromatiaceae › Nitrosococcus › Nitrosococcus oceani

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity. HAMAP-Rule MF_00712 SAAS SAAS023010
Catalytic activity	Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2. HAMAP-Rule MF_00712 SAAS SAAS023010
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits By similarity. HAMAP-Rule MF_00712 SAAS SAAS023010
Sequence similarities	Belongs to the GcvP family. N-terminal subunit subfamily. HAMAP-Rule MF_00712

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP-Rule MF_00712 SAAS SAAS023010 EMBL ABA57420.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP nucleoside metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glycine dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3JCM6 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 1A63F957578F4370	FASTA	452	48,712
	10 20 30 40 50 60 MPFIPHTDED IRAMLATAGV PDIETLFDEI PADLRTTDFD AVPPGLNEME VSRLLQERAA 70 80 90 100 110 120 QNRPTVCFAG GGAYQHHIPA AVWEITSRGE YYSAYTPYQA EASQGTLQVI YEYQSMMTAL 130 140 150 160 170 180 TGMEVSNASI YDGASALGEA VLMAVRLSRR GKSSCVLLPA TVHPAYRQVV ATLVGDQGIS 190 200 210 220 230 240 LQEISYDFGS GVVEPETLES IQKDFAALVI PQPNYFGCLE EVDTLTNWAH ERGALVIGVV 250 260 270 280 290 300 NPTSLALLKP PGEWGEAGAD IVCGEGQPLG IPLASGGPYF GFMACKQAHV RQLPGRIVGR 310 320 330 340 350 360 TVDLESKPGY TLTLQAREQH IRRSKATSNI CTNQGLMVTA ATLYMALLGP QGLAQVATAC 370 380 390 400 410 420 HANTMALVKR LTALPGVEQV FEKPFFHEAV LRFPVPASRV LSVLGQGGVL AGVKLEQAYP 430 440 450 ELNDTLLVCA TELRNEEDIE FYVRELTAAL AG

References

[1]

"Complete genome sequence of the marine, chemolithoautotrophic, ammonia-oxidizing bacterium Nitrosococcus oceani ATCC 19707." Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J., Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T., Vergez L.M., Ward B.B. Appl. Environ. Microbiol. 72:6299-6315(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19707 / NCIMB 11848.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000127 Genomic DNA. Translation: ABA57420.1.
RefSeq	YP_342950.1. NC_007484.1.
3D structure databases
ProteinModelPortal	Q3JCM6.
ModBase	Search...
Protein-protein interaction databases
STRING	323261.Noc_0908.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABA57420; ABA57420; Noc_0908.
GeneID	3707293.
KEGG	noc:Noc_0908.
PATRIC	22705686. VBINitOce57959_1082.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0403.
HOGENOM	HOG000132025.
KO	K00282.
OMA	MYDGASA.
ProtClustDB	PRK00451.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
HAMAP	MF_00712. GcvPA.
InterPro	IPR020580. GDC-P_N. IPR020581. GDC_P. IPR023010. GDC_P_su1. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11773. PTHR11773. 1 hit.
Pfam	PF02347. GDC-P. 1 hit. [Graphical view]
PIRSF	PIRSF006815. GcvPA. 1 hit.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3JCM6_NITOC

Accession

Primary (citable) accession number: Q3JCM6

Entry history

Integrated into UniProtKB/TrEMBL:	November 8, 2005
Last sequence update:	November 8, 2005
Last modified:	May 1, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)