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Q3JCM6 (Q3JCM6_NITOC) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable glycine dehydrogenase [decarboxylating] subunit 1 HAMAP-Rule MF_00712

EC=1.4.4.2 HAMAP-Rule MF_00712
Alternative name(s):
Glycine cleavage system P-protein subunit 1 HAMAP-Rule MF_00712
Glycine decarboxylase subunit 1 HAMAP-Rule MF_00712
Glycine dehydrogenase (aminomethyl-transferring) subunit 1 HAMAP-Rule MF_00712
Gene names
Name:gcvPA HAMAP-Rule MF_00712
Ordered Locus Names:Noc_0908 EMBL ABA57420.1
OrganismNitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) [Complete proteome] [HAMAP] EMBL ABA57420.1
Taxonomic identifier323261 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeNitrosococcus

Protein attributes

Sequence length452 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity. HAMAP-Rule MF_00712 SAAS SAAS023010

Catalytic activity

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2. HAMAP-Rule MF_00712 SAAS SAAS020581

Subunit structure

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits By similarity. HAMAP-Rule MF_00712 SAAS SAAS020581

Sequence similarities

Belongs to the GcvP family. N-terminal subunit subfamily. HAMAP-Rule MF_00712

Sequences

Sequence LengthMass (Da)Tools
Q3JCM6 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 1A63F957578F4370

FASTA45248,712
        10         20         30         40         50         60 
MPFIPHTDED IRAMLATAGV PDIETLFDEI PADLRTTDFD AVPPGLNEME VSRLLQERAA 

        70         80         90        100        110        120 
QNRPTVCFAG GGAYQHHIPA AVWEITSRGE YYSAYTPYQA EASQGTLQVI YEYQSMMTAL 

       130        140        150        160        170        180 
TGMEVSNASI YDGASALGEA VLMAVRLSRR GKSSCVLLPA TVHPAYRQVV ATLVGDQGIS 

       190        200        210        220        230        240 
LQEISYDFGS GVVEPETLES IQKDFAALVI PQPNYFGCLE EVDTLTNWAH ERGALVIGVV 

       250        260        270        280        290        300 
NPTSLALLKP PGEWGEAGAD IVCGEGQPLG IPLASGGPYF GFMACKQAHV RQLPGRIVGR 

       310        320        330        340        350        360 
TVDLESKPGY TLTLQAREQH IRRSKATSNI CTNQGLMVTA ATLYMALLGP QGLAQVATAC 

       370        380        390        400        410        420 
HANTMALVKR LTALPGVEQV FEKPFFHEAV LRFPVPASRV LSVLGQGGVL AGVKLEQAYP 

       430        440        450 
ELNDTLLVCA TELRNEEDIE FYVRELTAAL AG 

« Hide

References

[1]"Complete genome sequence of the marine, chemolithoautotrophic, ammonia-oxidizing bacterium Nitrosococcus oceani ATCC 19707."
Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J., Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T., Vergez L.M., Ward B.B.
Appl. Environ. Microbiol. 72:6299-6315(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 19707 / NCIMB 11848.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000127 Genomic DNA. Translation: ABA57420.1.
RefSeqYP_342950.1. NC_007484.1.

3D structure databases

ProteinModelPortalQ3JCM6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING323261.Noc_0908.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA57420; ABA57420; Noc_0908.
GeneID3707293.
KEGGnoc:Noc_0908.
PATRIC22705686. VBINitOce57959_1082.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0403.
HOGENOMHOG000132025.
KOK00282.
OMAFFHEAVL.
OrthoDBEOG6XWV3B.

Enzyme and pathway databases

BioCycNOCE323261:GCI3-917-MONOMER.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
HAMAPMF_00712. GcvPA.
InterProIPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR023010. GDC_P_su1.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERPTHR11773. PTHR11773. 1 hit.
PfamPF02347. GDC-P. 1 hit.
[Graphical view]
PIRSFPIRSF006815. GcvPA. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3JCM6_NITOC
AccessionPrimary (citable) accession number: Q3JCM6
Entry history
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)