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Protein

Pyruvate kinase

Gene

Noc_0990

Organism
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. potassium ion binding Source: InterPro
  3. pyruvate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciNOCE323261:GCI3-1005-MONOMER.
UniPathwayiUPA00109; UER00188.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinaseUniRule annotation (EC:2.7.1.40UniRule annotation)
Gene namesi
Ordered Locus Names:Noc_0990Imported
OrganismiNitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)Imported
Taxonomic identifieri323261 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeNitrosococcus
ProteomesiUP000006838: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi323261.Noc_0990.

Structurei

3D structure databases

ProteinModelPortaliQ3JCE7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0469.
HOGENOMiHOG000021558.
KOiK00873.
OMAiYLRRSSI.
OrthoDBiEOG6GBMB0.

Family and domain databases

Gene3Di2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSiPR01050. PYRUVTKNASE.
SUPFAMiSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsiTIGR01064. pyruv_kin. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3JCE7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MISKKQKKAD HEGDSPFKFE KDPRACRIVC TIGPASRSPA ILRKMLLSGM
60 70 80 90 100
NVARLNFSHG NHESHGRIAC EIREAAQRLM KPVAILQDLQ GHKVRVGKVQ
110 120 130 140 150
HPPSLSLEEG QEILLGHGET ISSKRIGIDY QDIIQYVTPG QKVFLDDASI
160 170 180 190 200
ELEVLSIEEK DLHCQVKFGG QLRSRKGVIF PDSQLSFPLL NEKDATDARF
210 220 230 240 250
GVFLDVDMVA MSFVRSATEI IEMRLRLAEW GQKNSFIIAK IEDHKGIDNL
260 270 280 290 300
DEILQVADGV LVARGDLGVT LPREKVPNIQ KAIIQKANAF GVPVITATQM
310 320 330 340 350
LESMTHHDIP TRAEVNDVYH AVIGGSDAVM LSGETASGRY PIQAVQEMNR
360 370 380 390 400
ICREAEKELR NVKGEIPVRG KQDMHDKMAA SAVNLAHNTK ARCILAFSLS
410 420 430 440 450
GATLRALSSA RSSVPVYGVV VEERLLRQLL LHWGHSLITM PHEETLENLI
460 470 480 490
CPALKQLQEE NIIHSNDRIV VMASQAEAGA KETYLFKLYL LE
Length:492
Mass (Da):54,627
Last modified:November 8, 2005 - v1
Checksum:iF6E9034266CDD879
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000127 Genomic DNA. Translation: ABA57499.1.
RefSeqiYP_343029.1. NC_007484.1.

Genome annotation databases

EnsemblBacteriaiABA57499; ABA57499; Noc_0990.
GeneIDi3707382.
KEGGinoc:Noc_0990.
PATRICi22705894. VBINitOce57959_1180.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000127 Genomic DNA. Translation: ABA57499.1.
RefSeqiYP_343029.1. NC_007484.1.

3D structure databases

ProteinModelPortaliQ3JCE7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi323261.Noc_0990.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA57499; ABA57499; Noc_0990.
GeneIDi3707382.
KEGGinoc:Noc_0990.
PATRICi22705894. VBINitOce57959_1180.

Phylogenomic databases

eggNOGiCOG0469.
HOGENOMiHOG000021558.
KOiK00873.
OMAiYLRRSSI.
OrthoDBiEOG6GBMB0.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00188.
BioCyciNOCE323261:GCI3-1005-MONOMER.

Family and domain databases

Gene3Di2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSiPR01050. PYRUVTKNASE.
SUPFAMiSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsiTIGR01064. pyruv_kin. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the marine, chemolithoautotrophic, ammonia-oxidizing bacterium Nitrosococcus oceani ATCC 19707."
    Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J., Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T., Vergez L.M., Ward B.B.
    Appl. Environ. Microbiol. 72:6299-6315(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19707 / NCIMB 11848Imported.

Entry informationi

Entry nameiQ3JCE7_NITOC
AccessioniPrimary (citable) accession number: Q3JCE7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: February 4, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.