Q3JA98 (Q3JA98_NITOC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 1 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 1 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 1 HAMAP MF_01401

Gene names

Name:	msrA1 HAMAP MF_01401
Ordered Locus Names:	Noc_1776

Organism

Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) [Complete proteome] [HAMAP] EMBL ABA58248.1

Taxonomic identifier

323261 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Chromatiaceae › Nitrosococcus

Protein attributes

Sequence length	212 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Domain	Signal EMBL ABA58248.1
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL ABA58248.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 33	33	Potential EMBL ABA58248.1
	Chain	34 – 212	179	Potential EMBL ABA58248.1		PRO_5000104768
Sites
	Active site	48	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q3JA98 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: C4AC6E48B780C69D	FASTA	212	23,981
	10 20 30 40 50 60 MTEKIKTREQ FLTHGLMVLC LVVLIGLRPA LALEAGKAPA KATFAGGCFW CMEPPFDNLE 70 80 90 100 110 120 GVISTTSGYI GGHMKNPTYE TVSGGKTGHA EAVQISYDPN QISYAELLAI FWRNIDPLAE 130 140 150 160 170 180 NRQFCDHGSQ YRSAIFYHNE TQQRLAEESK AQLAQSGRFN QPIVTEIKLA TQFYPAEAYH 190 200 210 QNYYQKNPIR YKLYRFGCGR DQRLQELWGD AS

References

[1]

"Complete genome sequence of the marine, chemolithoautotrophic, ammonia-oxidizing bacterium Nitrosococcus oceani ATCC 19707." Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J., Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T., Vergez L.M., Ward B.B. Appl. Environ. Microbiol. 72:6299-6315(2006) [PubMed: 16957257] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000127 Genomic DNA. Translation: ABA58248.1.
RefSeq	YP_343778.1. NC_007484.1.
3D structure databases
ProteinModelPortal	Q3JA98.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3JA98.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3704891.
GenomeReviews	Gene locus Noc_1776 in contig CP000127_GR.
KEGG	noc:Noc_1776.
NMPDR	fig|323261.3.peg.1248.
PATRIC	22707774. VBINitOce57959_2104.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	KIEYDVA.
PhylomeDB	Q3JA98.
ProtClustDB	CLSK940385.
Enzyme and pathway databases
BioCyc	NOCE323261:NOC_1776-MONOMER.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3JA98_NITOC

Accession

Primary (citable) accession number: Q3JA98

Entry history

Integrated into UniProtKB/TrEMBL:	November 8, 2005
Last sequence update:	November 8, 2005
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)