SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q3J9C8

- ASSY_NITOC

UniProt

Q3J9C8 - ASSY_NITOC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Argininosuccinate synthase
Gene
argG, Noc_2108
Organism
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei88 – 881Citrulline By similarity
Binding sitei93 – 931Citrulline By similarity
Binding sitei118 – 1181ATP; via amide nitrogen By similarity
Binding sitei120 – 1201Aspartate By similarity
Binding sitei124 – 1241Aspartate By similarity
Binding sitei124 – 1241Citrulline By similarity
Binding sitei125 – 1251Aspartate By similarity
Binding sitei128 – 1281Citrulline By similarity
Binding sitei179 – 1791Citrulline By similarity
Binding sitei188 – 1881Citrulline By similarity
Binding sitei264 – 2641Citrulline By similarity
Binding sitei276 – 2761Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. argininosuccinate synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNOCE323261:GCI3-2141-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:Noc_2108
OrganismiNitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Taxonomic identifieri323261 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeNitrosococcus
ProteomesiUP000006838: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 405405Argininosuccinate synthaseUniRule annotation
PRO_0000263944Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi323261.Noc_2108.

Structurei

3D structure databases

ProteinModelPortaliQ3J9C8.
SMRiQ3J9C8. Positions 6-400.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3J9C8-1 [UniParc]FASTAAdd to Basket

« Hide

MSTIKKVVLA YSGGLDTSVI LKWLQETYDC EVVTFTADIG QGEEVAPARA    50
KAETLGVKEI YIEDLREEFC RDYVFPMFRA NTLYEGEYLL GTSIARPLIA 100
KRLAEIASAT GADAVAHGAT GKGNDQVRFE LGVYALQPDI QVIAPWREWD 150
LTSREKLLAY AETHGIPVEG KRGGRSPYSM DANLLHISYE GGPLEDPWFE 200
PEESMWRWTT SPEASADQAA YLELDYRCGD IVAINGEVLS PAKVLESLNQ 250
LGSKHGIGRL DLVENRYVGM KSRGCYETPA GTIMLKAHRA LESLTLDREV 300
THLKDELMPR YANLIYNGYW WSPERSLLQQ LIDGSQVTVN GTVRLKLYKG 350
NVVVVGRRSE TDSLFAPEIA TFEDDAGAYN QQDAEGFIKL NALRLRIEAL 400
KKQTH 405
Length:405
Mass (Da):45,219
Last modified:November 8, 2005 - v1
Checksum:iB747B1A9617AB876
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000127 Genomic DNA. Translation: ABA58568.1.
RefSeqiYP_344098.1. NC_007484.1.

Genome annotation databases

EnsemblBacteriaiABA58568; ABA58568; Noc_2108.
GeneIDi3704418.
KEGGinoc:Noc_2108.
PATRICi22708550. VBINitOce57959_2490.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000127 Genomic DNA. Translation: ABA58568.1 .
RefSeqi YP_344098.1. NC_007484.1.

3D structure databases

ProteinModelPortali Q3J9C8.
SMRi Q3J9C8. Positions 6-400.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 323261.Noc_2108.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA58568 ; ABA58568 ; Noc_2108 .
GeneIDi 3704418.
KEGGi noc:Noc_2108.
PATRICi 22708550. VBINitOce57959_2490.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci NOCE323261:GCI3-2141-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the marine, chemolithoautotrophic, ammonia-oxidizing bacterium Nitrosococcus oceani ATCC 19707."
    Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J., Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T., Vergez L.M., Ward B.B.
    Appl. Environ. Microbiol. 72:6299-6315(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19707 / NCIMB 11848.

Entry informationi

Entry nameiASSY_NITOC
AccessioniPrimary (citable) accession number: Q3J9C8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: November 8, 2005
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi