Q3J7Z7 (LFTR_NITOC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase
EC=2.3.2.6

Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase

Gene names

Name:	aat
Ordered Locus Names:	Noc_2596

Organism

Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) [Complete proteome] [HAMAP]

Taxonomic identifier

323261 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Chromatiaceae › Nitrosococcus › Nitrosococcus oceani

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity. HAMAP-Rule MF_00688
Catalytic activity	L-leucyl-tRNA + protein = tRNA + L-leucyl-protein. HAMAP-Rule MF_00688 L-phenylalanyl-tRNA + protein = tRNA + L-phenylalanyl-protein. HAMAP-Rule MF_00688
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the L/F-transferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein catabolic process Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	leucyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 240	240	Leucyl/phenylalanyl-tRNA--protein transferase HAMAP-Rule MF_00688		PRO_0000258070

Sequences

	Sequence		Length	Mass (Da)
	Q3J7Z7 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 47F10ADC43E530BD	FASTA	240	27,746
	10 20 30 40 50 60 MEEFHCIDSN RLANAFPHPR LALAEPNGLL AVGGDLSPER LIMAYRQGIF PWYNQGQPIL 70 80 90 100 110 120 WWSPDPRLIL FPQQLHISRS LHKRLRRGIY QVTLDLDFPG VIQACASPRQ DGEGTWITSE 130 140 150 160 170 180 MKSAYNRLHE MGIAHSVETW EDKELIGGLY GVSIGRIFFG ESMFSKRPDA SKIAFVYLCR 190 200 210 220 230 240 QLQRWGFPLI DCQIQSEHLQ RLGAQTLPRN KFLHWLHEFS NSPSLKRPWH FDPDLLKNSL

References

[1]

"Complete genome sequence of the marine, chemolithoautotrophic, ammonia-oxidizing bacterium Nitrosococcus oceani ATCC 19707." Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J., Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T., Vergez L.M., Ward B.B. Appl. Environ. Microbiol. 72:6299-6315(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19707 / NCIMB 11848.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000127 Genomic DNA. Translation: ABA59049.1.
RefSeq	YP_344579.1. NC_007484.1.
3D structure databases
HSSP	HSSP built from PDB template 2CXA based on UniProtKB P0A8P1.
ProteinModelPortal	Q3J7Z7.
SMR	Q3J7Z7. Positions 14-229.
ModBase	Search...
Protein-protein interaction databases
STRING	323261.Noc_2596.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABA59049; ABA59049; Noc_2596.
GeneID	3704680.
KEGG	noc:Noc_2596.
PATRIC	22709646. VBINitOce57959_3025.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2360.
HOGENOM	HOG000102325.
KO	K00684.
OMA	MFYGESM.
ProtClustDB	PRK00301.
Family and domain databases
HAMAP	MF_00688. Leu_Phe_trans.
InterPro	IPR016181. Acyl_CoA_acyltransferase. IPR004616. Leu/Phe-tRNA_Trfase. [Graphical view]
Pfam	PF03588. Leu_Phe_trans. 1 hit. [Graphical view]
SUPFAM	SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMs	TIGR00667. aat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

LFTR_NITOC

Accession

Primary (citable) accession number: Q3J7Z7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	November 8, 2005
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program