Skip Header

 
Contribute Send feedback

Reviewed, UniProtKB/Swiss-Prot Q3J4E9 (BETB_RHOS4)

Last modified November 4, 2008. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Betaine aldehyde dehydrogenase
      Short name=BADH
    EC=1.2.1.8
Gene names
Name: betB
Ordered Locus Names: RHOS4_07670
ORF Names: RSP_2183
OrganismRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) [Complete proteome] [HAMAP]
Taxonomic identifier272943 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

Protein attributes

Sequence length483 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD(+) + H(2)O = betaine + NADH.

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords

   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome

Gene Ontology (GO)

   Biological processglycine betaine biosynthetic process from choline

Inferred from electronic annotation. Source: HAMAP

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 483483Betaine aldehyde dehydrogenase
PRO_1000047055

Regions

Nucleotide binding227 – 2326NAD By similarity

Sites

Active site2491 By similarity
Active site2831 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3J4E9-1 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 9BFC75AA2D687748

FASTA48350,804
        10         20         30         40         50         60 
MRAQPAASHF VDGRPLEDET GAPIPVIYPA TGEEIARLHE ATPAVIEAAL ASGARAQAAW 

        70         80         90        100        110        120 
AAMRPVERAR ILRRASDLIR AHNEELSLLE TLDTGKPLQE TLVADWASGA DALEFFAGLA 

       130        140        150        160        170        180 
PVVTGETVPL GQDFVYTIRE PLGLCVGIGA WNYPSQIACW KAAPALALGN AMVFKPSEVT 

       190        200        210        220        230        240 
PLGALKLAEI LIEAGLPPGL FNVVQGRGAV GASLVTDSRV AKVSLTGSVP TGRRVYAAAA 

       250        260        270        280        290        300 
EGVRHVTMEL GGKSPLIVFD DADLESAIGA AMLGNFYSAG QICSNGTRVF VQKGIKEAFL 

       310        320        330        340        350        360 
ARLAERADAI RMGDPLDPEV QMGPLVSQAQ LEKVLAYIEK ARAEGGRLVC GGEASVSPGC 

       370        380        390        400        410        420 
YVQPTVFADV TDAMTLAREE VFGPVMAVLD FETEEEAIAR ANATDFGLAA GVFTADLTRA 

       430        440        450        460        470        480 
HRVVAQLQAG TCWINAYNLT PVEAPFGGVK LSGVGRENGR AAVQHYTQVK SVYVGMGPVD 


APY 

« Hide

References

[1]"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000143 Genomic DNA. Translation: ABA78335.1.
RefSeqYP_352236.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3719653.
GenomeReviewsGene locus RHOS4_07670 in contig CP000143_GR.
KEGGrsp:RSP_2183.
NMPDRfig|272943.3.peg.1373.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ3J4E9.

Enzyme and pathway databases

BioCycRSPH272943:RSP_2183-MON.

Family and domain databases

HAMAPMF_00804.
[Tree]
InterProIPR016160. Ald_DHase_CS.
IPR016162. Ald_DHase_N.
IPR015590. Aldehyde_DHase.
IPR011264. Betaine_Ald_DHase.
[Graphical view]
Gene3DG3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
PANTHERPTHR11699. Aldehyde_dehyd. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
TIGRFAMsTIGR01804. BADH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETB_RHOS4
AccessionPrimary (citable) accession number: Q3J4E9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 8, 2005
Last modified: November 4, 2008
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents