Q3J4E8 (Q3J4E8_RHOS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Choline dehydrogenase EMBL ABA78336.1
EC=1.1.99.1 EMBL ABA78336.1

Gene names

Name:	betA EMBL ABA78336.1
Ordered Locus Names:	RHOS4_07680
ORF Names:	RSP_2184 EMBL ABA78336.1

Organism

Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) EMBL ABA78336.1

Taxonomic identifier

272943 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	548 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. SAAS SAAS007867
Catalytic activity	Choline + acceptor = betaine aldehyde + reduced acceptor. SAAS SAAS007867
Cofactor	FAD By similarity. SAAS SAAS007867
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. SAAS SAAS007867

Ontologies

Keywords
Ligand	FAD SAAS SAAS011533 Flavoprotein SAAS SAAS011533
Molecular function	Oxidoreductase SAAS SAAS007867 EMBL ABA78336.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3J4E8 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 9C7E1FD7C34843F2	FASTA	548	59,980
	10 20 30 40 50 60 MFDYIIVGAG SAGCAMAYRL GEAGRSVLVI EHGGTDAGPF IQMPAALSYP MNMGIYDWGL 70 80 90 100 110 120 KTEPEPHLDG RVLATPRGKV IGGSSSINGM VYVRGHARDF DHWAESGATG WGFADVLPYF 130 140 150 160 170 180 KRMENWHVPG DVEWRGHDGP LHVTRGPRSN PLFNAFIEAG RQAGYPVTDD YNGAAQEGFG 190 200 210 220 230 240 PMEATIWQGR RWSAANAYLR PAMKRFGVQL TRALALKVVI EEGRAVGVEV QRRGGREVIR 250 260 270 280 290 300 AGREVILAAS SLNTPKLLML SGIGSAAHLA EHGIPVVADR PGVGQNLQDH LEVYMQFASL 310 320 330 340 350 360 QPVTLFKHWN LRGKVSIGAQ WLFTGRGLGA SNQFEACAFI RSKPGVEYPD IQYHFLPIAV 370 380 390 400 410 420 RYDGKAAAEG HGFQVHVGPM RSPSRGSVTL RSADPEAPPV IRFNYMSTEE DWQDFRRCVR 430 440 450 460 470 480 LTREIFGQEA FKPFVRHEIQ PGAACASDAE IDAFIREHVE SAYHPCGTAR IGRADDPMAV 490 500 510 520 530 540 VDPECRVIGV EGLRVADSSI FPRVTNGNLN APSIMVGEKA SDHILGRTPL APLNLEPVTN PNWRTAQR

References

[1]

"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000143 Genomic DNA. Translation: ABA78336.1.
RefSeq	YP_352237.1. NC_007493.1.
3D structure databases
ProteinModelPortal	Q3J4E8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3J4E8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3719654.
GenomeReviews	Gene locus RHOS4_07680 in contig CP000143_GR.
KEGG	rsp:RSP_2184.
NMPDR	fig|272943.3.peg.1374.
PATRIC	23151372. VBIRhoSph57909_1080.
Phylogenomic databases
eggNOG	COG2303.
HOGENOM	HBG734713.
OMA	GPFIQMP.
PhylomeDB	Q3J4E8.
ProtClustDB	PRK02106.
Enzyme and pathway databases
BioCyc	RSPH272943:RSP_2184-MONOMER.
Family and domain databases
InterPro	IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
KO	K00108.
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMs	TIGR01810. BetA. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q3J4E8_RHOS4

Accession

Primary (citable) accession number: Q3J4E8

Entry history

Integrated into UniProtKB/TrEMBL:	November 8, 2005
Last sequence update:	November 8, 2005
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)