Q3J281 (SYR_RHOS4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase
EC=6.1.1.19

Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	RHOS4_15350
ORF Names:	RSP_2943

Organism

Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) [Reference proteome] [HAMAP]

Taxonomic identifier

272943 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter › Rhodobacter sphaeroides

Protein attributes

Sequence length	583 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 583	583	Arginine--tRNA ligase HAMAP-Rule MF_00123		PRO_0000242077
Regions
	Motif	134 – 144	11	"HIGH" region HAMAP-Rule MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q3J281 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: F2C83A5C90A605F2	FASTA	583	64,069
	10 20 30 40 50 60 MPRMNLFTEI RTLVTAELGA MTEAGDLPAG LDLSAVAVEP PRDPAHGDMS TNAAMVLAKP 70 80 90 100 110 120 SGKPPRTIAE ALATRLAADP RISSAEVAGP GFLNLRLRPA VWQGMVATIL QAGDTYGRST 130 140 150 160 170 180 IGAGQKVNVE FVSANPTGPM HVGHVRGAVV GDALARLLAY AGWNVTREYY INDGGAQVDV 190 200 210 220 230 240 LARSAFERYR EAHGLEPEIR EGLYPGDYLI PVGEALKAKY GDSLLDKGEQ HWLTEVREFA 250 260 270 280 290 300 TEMMMQMIRE DLAALGVEMD VYSSEKALYG TGKIEAALDR LKEMDLIYEG VLEPPKGKTP 310 320 330 340 350 360 EDWEPREQTL FRSTAHGDDV DRPVKKSDGS WTYFAPDIAY HYDKVTRGFD QLIDIFGADH 370 380 390 400 410 420 GGYVKRMKAA VAALSAGRVP LDIKLIQLVK LWKNGEPFKM SKRAGTYVTL RDVVEQVGTD 430 440 450 460 470 480 VTRFVMLTRK NDATLDFDFD KVLEQSKENP VFYVQYANAR INSVLRKARE QGMDVSDATL 490 500 510 520 530 540 ATADLDRLDH PAEIALIAKL AEWPRLVEIA ARTNEPHRVA FYLHELASEL HGLWNRGNDE 550 560 570 580 AGLRFLQDDP VVSQAKIALA RAVGVVICAG LGILGVTPVE EMR

References

[1]

"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000143 Genomic DNA. Translation: ABA79103.1.
RefSeq	YP_353004.1. NC_007493.1.
3D structure databases
ProteinModelPortal	Q3J281.
ModBase	Search...
Protein-protein interaction databases
STRING	272943.RSP_2943.
Protocols and materials databases
DNASU	3720683.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3720683.
KEGG	rsp:RSP_2943.
PATRIC	23152989. VBIRhoSph57909_1880.
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HOG000247214.
KO	K01887.
OMA	HTSANPN.
ProtClustDB	PRK01611.
Enzyme and pathway databases
BioCyc	RSPH272943:GJAS-1571-MONOMER.
Family and domain databases
Gene3D	3.30.1360.70. 1 hit. 3.40.50.620. 1 hit.
HAMAP	MF_00123. Arg_tRNA_synth.
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
PANTHER	PTHR11956. PTHR11956. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_RHOS4

Accession

Primary (citable) accession number: Q3J281

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	November 8, 2005
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program