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Q3J281 (SYR_RHOS4) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:RHOS4_15350
ORF Names:RSP_2943
OrganismRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) [Reference proteome] [HAMAP]
Taxonomic identifier272943 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

Protein attributes

Sequence length580 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 580580Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242077

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q3J281 [UniParc].

Last modified February 19, 2014. Version 2.
Checksum: 5104EADECB01DE64

FASTA58063,685
        10         20         30         40         50         60 
MNLFTEIRTL VTAELGAMTE AGDLPAGLDL SAVAVEPPRD PAHGDMSTNA AMVLAKPSGK 

        70         80         90        100        110        120 
PPRTIAEALA TRLAADPRIS SAEVAGPGFL NLRLRPAVWQ GMVATILQAG DTYGRSTIGA 

       130        140        150        160        170        180 
GQKVNVEFVS ANPTGPMHVG HVRGAVVGDA LARLLAYAGW NVTREYYIND GGAQVDVLAR 

       190        200        210        220        230        240 
SAFERYREAH GLEPEIREGL YPGDYLIPVG EALKAKYGDS LLDKGEQHWL TEVREFATEM 

       250        260        270        280        290        300 
MMQMIREDLA ALGVEMDVYS SEKALYGTGK IEAALDRLKE MDLIYEGVLE PPKGKTPEDW 

       310        320        330        340        350        360 
EPREQTLFRS TAHGDDVDRP VKKSDGSWTY FAPDIAYHYD KVTRGFDQLI DIFGADHGGY 

       370        380        390        400        410        420 
VKRMKAAVAA LSAGRVPLDI KLIQLVKLWK NGEPFKMSKR AGTYVTLRDV VEQVGTDVTR 

       430        440        450        460        470        480 
FVMLTRKNDA TLDFDFDKVL EQSKENPVFY VQYANARINS VLRKAREQGM DVSDATLATA 

       490        500        510        520        530        540 
DLDRLDHPAE IALIAKLAEW PRLVEIAART NEPHRVAFYL HELASELHGL WNRGNDEAGL 

       550        560        570        580 
RFLQDDPVVS QAKIALARAV GVVICAGLGI LGVTPVEEMR 

« Hide

References

[1]"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000143 Genomic DNA. Translation: ABA79103.2.
RefSeqYP_353004.2. NC_007493.2.

3D structure databases

ProteinModelPortalQ3J281.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272943.RSP_2943.

Protocols and materials databases

DNASU3720683.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA79103; ABA79103; RSP_2943.
GeneID3720683.
KEGGrsp:RSP_2943.
PATRIC23152989. VBIRhoSph57909_1880.

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMARFIMLTR.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycRSPH272943:GJAS-1571-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_RHOS4
AccessionPrimary (citable) accession number: Q3J281
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: February 19, 2014
Last modified: April 16, 2014
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries