Q3J149 (URED_RHOS4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease accessory protein UreD

Gene names

Name:	ureD
Ordered Locus Names:	RHOS4_19170
ORF Names:	RSP_0310

Organism

Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

Taxonomic identifier

272943 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01384
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01384.
Sequence similarities	Belongs to the UreD family.
Sequence caution	The sequence AAF24251.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 275	275	Urease accessory protein UreD HAMAP MF_01384		PRO_0000340505
Experimental info
	Sequence conflict	51	1	V → VLVM in AAF24251. Ref.1
	Sequence conflict	126	1	A → P in AAF24251. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q3J149 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: BB0FF197520FB0C8	FASTA	275	28,742
	10 20 30 40 50 60 MNALTPLSAR LERSDGHALV TLARSRGAVR LRDLAQRGSA KAFLPRVEGD VPEVVFLNTS 70 80 90 100 110 120 GGLTGGDRLS YRLEVGEGCR ATATTQTAER AYAAGAGAAR VEVLHEVGRD GWLDWLPQET 130 140 150 160 170 180 ILFEGAALER ETQISLAPGA GCLMVESVVL GRAAMGETLS RLAFRDRRSI LRGGKPVVVE 190 200 210 220 230 240 PLALDDRALA AAGGAAMLGG ARALATLAMV GPGAEDALGP ARAALGEAGV EAAASAFDGK 250 260 270 LVLRLLAADG WPLRRQVARL LTVLRGRALP RVWQV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence analysis of the photosynthesis region of Rhodobacter sphaeroides 2.4.1." Choudhary M., Kaplan S. Nucleic Acids Res. 28:862-867(2000) [PubMed: 10648776] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF195122 Genomic DNA. Translation: AAF24251.1. Different initiation. CP000143 Genomic DNA. Translation: ABA79485.1.
RefSeq	YP_353386.1. NC_007493.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q3J149.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3719166.
GenomeReviews	Gene locus RHOS4_19170 in contig CP000143_GR.
KEGG	rsp:RSP_0310.
NMPDR	fig|272943.3.peg.1718.
PATRIC	23153764. VBIRhoSph57909_2257.
Phylogenomic databases
eggNOG	COG0829.
HOGENOM	HBG711156.
OMA	QETILFD.
ProtClustDB	CLSK940836.
Enzyme and pathway databases
BioCyc	RSPH272943:RSP_0310-MONOMER.
Family and domain databases
HAMAP	MF_01384. UreD. [Tree]
InterPro	IPR002669. UreD. [Graphical view]
KO	K03190.
Pfam	PF01774. UreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

URED_RHOS4

Accession

Primary (citable) accession number: Q3J149
Secondary accession number(s): Q9RFF6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	November 8, 2005
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program