Q3IZH9 (Q3IZH9_RHOS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163

Gene names

Name:	def1 HAMAP MF_00163
Ordered Locus Names:	RHOS4_24870
ORF Names:	RSP_0872 EMBL ABA80055.1

Organism

Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) EMBL ABA80055.1

Taxonomic identifier

272943 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. HAMAP MF_00163

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00163 SAAS SAAS000181
Ligand	Iron HAMAP MF_00163 Metal-binding HAMAP MF_00163 SAAS SAAS000181
Molecular function	Hydrolase SAAS SAAS000181 HAMAP MF_00163 EMBL ABA80055.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	137	1	By similarity HAMAP MF_00163
	Metal binding	94	1	Iron By similarity HAMAP MF_00163
	Metal binding	136	1	Iron By similarity HAMAP MF_00163
	Metal binding	140	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	Q3IZH9 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 4C0DAF1618ED746D	FASTA	177	20,083
	10 20 30 40 50 60 MIRPILIHPD PRLKKICDPV GQITDDLRRL ADDMLATMYD APGIGLAAPQ VGVVRRLIVL 70 80 90 100 110 120 DCNKESDGAR RPVAMVNPEV VWRSEDVSTY EEGCLSLPNV FADVERPAEV KVRWTGLDGR 130 140 150 160 170 EEEEQFAGLW ATCVQHEIDH LDGKLFIDYL RPLKRQMITR KMEKFKRAQA SGMVQKA

References

[1]

"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000143 Genomic DNA. Translation: ABA80055.1.
RefSeq	YP_353956.1. NC_007493.1.
3D structure databases
ProteinModelPortal	Q3IZH9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3IZH9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3718226.
GenomeReviews	Gene locus RHOS4_24870 in contig CP000143_GR.
KEGG	rsp:RSP_0872.
NMPDR	fig|272943.3.peg.2636.
PATRIC	23154939. VBIRhoSph57909_2838.
Phylogenomic databases
eggNOG	COG0242.
HOGENOM	HBG665227.
OMA	QKIVDDM.
PhylomeDB	Q3IZH9.
ProtClustDB	CLSK934098.
Enzyme and pathway databases
BioCyc	RSPH272943:RSP_0872-MONOMER.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3IZH9_RHOS4

Accession

Primary (citable) accession number: Q3IZH9

Entry history

Integrated into UniProtKB/TrEMBL:	November 8, 2005
Last sequence update:	November 8, 2005
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)