Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ubiquinone biosynthesis O-methyltransferase

Gene

ubiG

Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n.UniRule annotation
S-adenosyl-L-methionine + 3-(all-trans-polyprenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + 2-methoxy-6-(all-trans-polyprenyl)phenol.UniRule annotation

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391S-adenosyl-L-methionineUniRule annotation
Binding sitei70 – 701S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
Binding sitei91 – 911S-adenosyl-L-methionineUniRule annotation
Binding sitei134 – 1341S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Ubiquinone biosynthesis

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciRSPH272943:GJAS-2856-MONOMER.
UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquinone biosynthesis O-methyltransferaseUniRule annotation
Alternative name(s):
2-polyprenyl-6-hydroxyphenol methylaseUniRule annotation (EC:2.1.1.222UniRule annotation)
3-demethylubiquinone 3-O-methyltransferaseUniRule annotation (EC:2.1.1.64UniRule annotation)
Gene namesi
Name:ubiGUniRule annotation
Ordered Locus Names:RHOS4_27910, RSP_1175
OrganismiRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Taxonomic identifieri272943 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
Proteomesi
  • UP000002703 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 247247Ubiquinone biosynthesis O-methyltransferasePRO_0000241726Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272943.RSP_1175.

Structurei

3D structure databases

ProteinModelPortaliQ3IYM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. UbiG/COQ3 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108HWB. Bacteria.
COG2227. LUCA.
HOGENOMiHOG000278064.
KOiK00568.
OMAiHDWEKFV.
OrthoDBiPOG091H064Z.
PhylomeDBiQ3IYM5.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00472. UbiG. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR010233. UbiG_MeTrfase.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR01983. UbiG. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3IYM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESSSTIDPA EVAKFEAMAA EWWNPHGKFK PLHQMNPCRL DYITQQIAAE
60 70 80 90 100
FDRDLSAPLP FEGLRLLDIG CGGGLLSEPM ARLGAEVIGA DAAPRNIPVA
110 120 130 140 150
KLHAEQSGLT IDYRNTTAEA LAAAGERFDV VLNMEVVEHV ADPLTYLTAC
160 170 180 190 200
RELLKPGGLM ICSTLNRNPK SFAMAIVGAE WVMRWLPKGT HDWSKFITPD
210 220 230 240
ELYDLIRKAG LDPVDRKGMV FNPVSWSWSL SARDLSVNYV TASVRRS
Length:247
Mass (Da):27,285
Last modified:November 8, 2005 - v1
Checksum:iC707748E68CD5DC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000143 Genomic DNA. Translation: ABA80359.1.
RefSeqiWP_011338766.1. NZ_AKVW01000001.1.
YP_354260.1. NC_007493.2.

Genome annotation databases

EnsemblBacteriaiABA80359; ABA80359; RSP_1175.
GeneIDi3718168.
KEGGirsp:RSP_1175.
PATRICi23155579. VBIRhoSph57909_3154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000143 Genomic DNA. Translation: ABA80359.1.
RefSeqiWP_011338766.1. NZ_AKVW01000001.1.
YP_354260.1. NC_007493.2.

3D structure databases

ProteinModelPortaliQ3IYM5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272943.RSP_1175.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA80359; ABA80359; RSP_1175.
GeneIDi3718168.
KEGGirsp:RSP_1175.
PATRICi23155579. VBIRhoSph57909_3154.

Phylogenomic databases

eggNOGiENOG4108HWB. Bacteria.
COG2227. LUCA.
HOGENOMiHOG000278064.
KOiK00568.
OMAiHDWEKFV.
OrthoDBiPOG091H064Z.
PhylomeDBiQ3IYM5.

Enzyme and pathway databases

UniPathwayiUPA00232.
BioCyciRSPH272943:GJAS-2856-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00472. UbiG. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR010233. UbiG_MeTrfase.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR01983. UbiG. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUBIG_RHOS4
AccessioniPrimary (citable) accession number: Q3IYM5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 8, 2005
Last modified: September 7, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.