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Protein

Xylose isomerase

Gene

xylA

Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei99UniRule annotation1
Active sitei102UniRule annotation1
Metal bindingi230Magnesium 1UniRule annotation1
Metal bindingi266Magnesium 1UniRule annotation1
Metal bindingi266Magnesium 2UniRule annotation1
Metal bindingi269Magnesium 2UniRule annotation1
Metal bindingi294Magnesium 1UniRule annotation1
Metal bindingi305Magnesium 2UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi337Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:RHOS4_27920
ORF Names:RSP_1176
OrganismiRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Taxonomic identifieri272943 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
Proteomesi
  • UP000002703 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002369691 – 433Xylose isomeraseAdd BLAST433

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi272943.RSP_1176

Structurei

3D structure databases

ProteinModelPortaliQ3IYM4
SMRiQ3IYM4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC
PhylomeDBiQ3IYM4

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q3IYM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDFFAGIPQ IRYEGEGSSN EFAFRHYNPD EVILGKRMED HLRFAVAWWH
60 70 80 90 100
SFAWPGGDPF GGQTFDRPWF GDTLDLAKLK ADVAFEMFDI LGAPFFCFHD
110 120 130 140 150
ADIRPEGATF AESKRNLEEI VDHIGIRMEG SKTKLLWGTA NLFSHRRFMS
160 170 180 190 200
GAATNPDPDV FAWSAATVKG CMDATMKLGG ANYVLWGGRE GYETLLNTDL
210 220 230 240 250
TREAENAGRF LQMVVDYKHK IGFQGTILIE PKPQEPSKHQ YDYDVATVYG
260 270 280 290 300
FLKRFGLEKE VKLNIEQGHA ILAGHSFEHE LALAASLGIL GSIDMNRNDY
310 320 330 340 350
QSGWDTDQFP HNHPEMALAY YEILRAGGFT TGGTNFDAKI RRQSLDPEDL
360 370 380 390 400
VLAHVGGMDT CARALKAAAR LYEDGSLETA RAARYAGWET PEAQAMLASS
410 420 430
LEKIEARVLA EGINPEPRSG RQERLENLWN RFV
Length:433
Mass (Da):48,563
Last modified:November 8, 2005 - v1
Checksum:i9577F5D500649F3D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000143 Genomic DNA Translation: ABA80360.1
RefSeqiWP_011338767.1, NZ_AKVW01000001.1
YP_354261.1, NC_007493.2

Genome annotation databases

EnsemblBacteriaiABA80360; ABA80360; RSP_1176
GeneIDi3718169
KEGGirsp:RSP_1176
PATRICifig|272943.9.peg.3155

Similar proteinsi

Entry informationi

Entry nameiXYLA_RHOS4
AccessioniPrimary (citable) accession number: Q3IYM4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 8, 2005
Last modified: April 25, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health