Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q3IYM4 (XYLA_RHOS4) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Xylose isomerase

EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:RHOS4_27920
ORF Names:RSP_1176
OrganismRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) [Reference proteome] [HAMAP]
Taxonomic identifier272943 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

Protein attributes

Sequence length433 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylopyranose = D-xylulose. HAMAP-Rule MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP-Rule MF_00455

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00455

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 433433Xylose isomerase HAMAP-Rule MF_00455
PRO_0000236969

Sites

Active site991 By similarity
Active site1021 By similarity
Metal binding2301Magnesium 1 By similarity
Metal binding2661Magnesium 1 By similarity
Metal binding2661Magnesium 2 By similarity
Metal binding2691Magnesium 2 By similarity
Metal binding2941Magnesium 1 By similarity
Metal binding3051Magnesium 2 By similarity
Metal binding3071Magnesium 2 By similarity
Metal binding3371Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3IYM4 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 9577F5D500649F3D

FASTA43348,563
        10         20         30         40         50         60 
MTDFFAGIPQ IRYEGEGSSN EFAFRHYNPD EVILGKRMED HLRFAVAWWH SFAWPGGDPF 

        70         80         90        100        110        120 
GGQTFDRPWF GDTLDLAKLK ADVAFEMFDI LGAPFFCFHD ADIRPEGATF AESKRNLEEI 

       130        140        150        160        170        180 
VDHIGIRMEG SKTKLLWGTA NLFSHRRFMS GAATNPDPDV FAWSAATVKG CMDATMKLGG 

       190        200        210        220        230        240 
ANYVLWGGRE GYETLLNTDL TREAENAGRF LQMVVDYKHK IGFQGTILIE PKPQEPSKHQ 

       250        260        270        280        290        300 
YDYDVATVYG FLKRFGLEKE VKLNIEQGHA ILAGHSFEHE LALAASLGIL GSIDMNRNDY 

       310        320        330        340        350        360 
QSGWDTDQFP HNHPEMALAY YEILRAGGFT TGGTNFDAKI RRQSLDPEDL VLAHVGGMDT 

       370        380        390        400        410        420 
CARALKAAAR LYEDGSLETA RAARYAGWET PEAQAMLASS LEKIEARVLA EGINPEPRSG 

       430 
RQERLENLWN RFV 

« Hide

References

[1]"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000143 Genomic DNA. Translation: ABA80360.1.
RefSeqYP_354261.1. NC_007493.2.

3D structure databases

ProteinModelPortalQ3IYM4.
SMRQ3IYM4. Positions 2-433.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272943.RSP_1176.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA80360; ABA80360; RSP_1176.
GeneID3718169.
KEGGrsp:RSP_1176.
PATRIC23155581. VBIRhoSph57909_3155.

Phylogenomic databases

eggNOGCOG2115.
HOGENOMHOG000252293.
KOK01805.
OMAKADSAFE.
OrthoDBEOG62NX4R.
PhylomeDBQ3IYM4.

Enzyme and pathway databases

BioCycRSPH272943:GJAS-2857-MONOMER.

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. SSF51658. 1 hit.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_RHOS4
AccessionPrimary (citable) accession number: Q3IYM4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 8, 2005
Last modified: July 9, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families