Q3IYH5 (RSMG_RHOS4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase G
EC=2.1.1.170

Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase

Gene names

Name:	rsmG
Ordered Locus Names:	RHOS4_28410
ORF Names:	RSP_1228

Organism

Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

Taxonomic identifier

272943 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the N7 position of guanosine in position 527 of 16S rRNA By similarity. HAMAP MF_00074
Catalytic activity	S-adenosyl-L-methionine + guanosine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanosine(527) in 16S rRNA. HAMAP MF_00074
Subcellular location	Cytoplasm Potential HAMAP MF_00074.
Sequence similarities	Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 206	206	Ribosomal RNA small subunit methyltransferase G HAMAP MF_00074		PRO_0000335410

Sequences

	Sequence		Length	Mass (Da)
	Q3IYH5 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 6BF63908C6528D31	FASTA	206	22,336
	10 20 30 40 50 60 MMQESVLAQL DVSRETSEKL SHFVALVEKW NKAVNLIGRS TVDSIWTRHV LDSAQLRTHL 70 80 90 100 110 120 ASQPRLWLDL GSGSGFPGIV VAIMAAYESP ESRFVLVESD QRKATFLRTA CRELKLSASV 130 140 150 160 170 180 LAARIESLPP QKADVISARA LAALPDLCAL AAPHLAPNGI CLFPKGVGHI SEIAAARQSW 190 200 NMEVETLPSL TDPDAVILKL KALAHV

References

[1]

"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000143 Genomic DNA. Translation: ABA80409.1.
RefSeq	YP_354310.1. NC_007493.1.
3D structure databases
ProteinModelPortal	Q3IYH5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3IYH5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3719676.
GenomeReviews	Gene locus RHOS4_28410 in contig CP000143_GR.
KEGG	rsp:RSP_1228.
NMPDR	fig|272943.3.peg.2721.
PATRIC	23155689. VBIRhoSph57909_3209.
Phylogenomic databases
eggNOG	COG0357.
HOGENOM	HBG686577.
OMA	CALAAPH.
PhylomeDB	Q3IYH5.
ProtClustDB	CLSK841446.
Enzyme and pathway databases
BioCyc	RSPH272943:RSP_1228-MONOMER.
Family and domain databases
HAMAP	MF_00074. 16SrRNA_methyltr_G. [Tree]
InterPro	IPR003682. rRNA_ssu_MeTfrase_G. [Graphical view]
KO	K03501.
Pfam	PF02527. GidB. 1 hit. [Graphical view]
PIRSF	PIRSF003078. GidB. 1 hit.
TIGRFAMs	TIGR00138. GidB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RSMG_RHOS4

Accession

Primary (citable) accession number: Q3IYH5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	November 8, 2005
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program