ID   Q3IXS8_CERS4            Unreviewed;       365 AA.
AC   Q3IXS8;
DT   08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 130.
DE   RecName: Full=Spermidine/putrescine import ATP-binding protein PotA {ECO:0000256|RuleBase:RU364083};
DE            EC=7.6.2.11 {ECO:0000256|RuleBase:RU364083};
GN   Name=potA {ECO:0000256|RuleBase:RU364083};
GN   ORFNames=RSP_3041 {ECO:0000313|EMBL:ABA80656.1};
OS   Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS   31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Cereibacter.
OX   NCBI_TaxID=272943 {ECO:0000313|EMBL:ABA80656.1, ECO:0000313|Proteomes:UP000002703};
RN   [1] {ECO:0000313|Proteomes:UP000002703}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC
RC   12203 / NCIMB 8253 / ATH 2.4.1. {ECO:0000313|Proteomes:UP000002703};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA   Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome 2 of Rhodobacter sphaeroides 2.4.1.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the ABC transporter complex PotABCD involved in
CC       spermidine/putrescine import. Responsible for energy coupling to the
CC       transport system. {ECO:0000256|RuleBase:RU364083}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + polyamine-[polyamine-binding protein]Side 1 = ADP
CC         + phosphate + polyamineSide 2 + [polyamine-binding protein]Side 1.;
CC         EC=7.6.2.11; Evidence={ECO:0000256|RuleBase:RU364083};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (PotA),
CC       two transmembrane proteins (PotB and PotC) and a solute-binding protein
CC       (PotD). {ECO:0000256|RuleBase:RU364083}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Spermidine/putrescine importer (TC 3.A.1.11.1) family.
CC       {ECO:0000256|RuleBase:RU364083}.
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DR   EMBL; CP000144; ABA80656.1; -; Genomic_DNA.
DR   RefSeq; YP_354557.1; NC_007494.2.
DR   AlphaFoldDB; Q3IXS8; -.
DR   STRING; 272943.RSP_3041; -.
DR   EnsemblBacteria; ABA80656; ABA80656; RSP_3041.
DR   KEGG; rsp:RSP_3041; -.
DR   PATRIC; fig|272943.9.peg.3459; -.
DR   eggNOG; COG3842; Bacteria.
DR   OrthoDB; 9802264at2; -.
DR   PhylomeDB; Q3IXS8; -.
DR   Proteomes; UP000002703; Chromosome 2.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0015417; F:ABC-type polyamine transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005893; PotA-like.
DR   InterPro; IPR013611; Transp-assoc_OB_typ2.
DR   NCBIfam; TIGR01187; potA; 1.
DR   PANTHER; PTHR42781; SPERMIDINE/PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA; 1.
DR   PANTHER; PTHR42781:SF4; SPERMIDINE_PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08402; TOBE_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; MOP-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU364083};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU364083};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364083};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU364083};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002703};
KW   Translocase {ECO:0000256|ARBA:ARBA00022967, ECO:0000256|RuleBase:RU364083};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU364083}.
FT   DOMAIN          12..244
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
SQ   SEQUENCE   365 AA;  39444 MW;  E3D0EDE28967ACEB CRC64;
     MVGHRMQSQP IAELRNVTKR YGLVTAATNL TLAIEPGEFL SFLGPSGCGK TTALRMLAGF
     EQASEGQVLI DGRDATALPA WQRPVNMVFQ QYALFPHLTV AQNVGYGLNQ RRPKPPRAEV
     AAAVDEALAL VQLSGFGARR TWELSGGQQQ RVALARAIVN KPKILLLDEP MAALDKKLRH
     DMQIELKSLQ RELGITFVLV THDQEEALSM SDRIVIMDHG RIAQIGGPEE LYDRPQSRYV
     ADFVGRSNFI GATGRGREAE ILVAEAGGLI FHARGGEKIG PGSPVTLSLR PEEIRLAPSG
     EGHRMVVTHR IFLGEHTEYH LTSGALPHLV AVVPRTAEAG SALLAPGAEV MASWRDGAAL
     ALDAG
//