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Q3IXK6 (DADA_RHOS4) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1
Gene names
Name:dadA
Ordered Locus Names:RHOS4_31600
ORF Names:RSP_3113
OrganismRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Taxonomic identifier272943 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length436 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202

Catalytic activity

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202

Cofactor

FAD By similarity. HAMAP MF_01202

Pathway

Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 436436D-amino acid dehydrogenase small subunit HAMAP MF_01202
PRO_1000066112

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
Q3IXK6 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: CAE52B673FC38B0B

FASTA43646,151
        10         20         30         40         50         60 
MRIVVLGAGV VGVTSAYELA RAGHEVTVVD RQPAAALETS FANAGEISPG YASPWAAPGI 

        70         80         90        100        110        120 
PAKALRWMFM KHAPLVIRPR LDAAQVRFLL AILRNCTPAA YAQNKGRMVR LAEYSRDCLT 

       130        140        150        160        170        180 
DLRATTGLAF DERQQGTLQL FRSQKQLDAA ARDIEVLRAG GVPFELLDAD GCLAAEPGLR 

       190        200        210        220        230        240 
AARDRIAGGL RLTGDETGDC FKFTQGLAGL AEEGGVRFRY GTGVERLRVE GGRVTGVETT 

       250        260        270        280        290        300 
KGTFLADAVV VALGSHSPAL VAPLGLRLPV YPVKGYSITV PIVDADRAPV STVMDETYKI 

       310        320        330        340        350        360 
AITRLGTRIR VGGMAEVAGF SATLPPARRE TLAMSVNDLF GGAGDLSRAS FWTGLRPMTP 

       370        380        390        400        410        420 
DGTPVVGRTP VAGLWLNTGH GTLGWTMAAG SARVLSDLID GRAPEIESAD LGIERYAAPG 

       430 
RRARPAVRLN PARQAG

« Hide

References

[1]"Complete sequence of chromosome 2 of Rhodobacter sphaeroides 2.4.1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000144 Genomic DNA. Translation: ABA80728.1.
RefSeqYP_354629.1. NC_007494.1.

3D structure databases

ProteinModelPortalQ3IXK6.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3IXK6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3721388.
GenomeReviewsGene locus RHOS4_31600 in contig CP000144_GR.
KEGGrsp:RSP_3113.
NMPDRfig|272943.3.peg.3123.
PATRIC23156381. VBIRhoSph57909_3539.

Phylogenomic databases

eggNOGCOG0665.
HOGENOMHBG729204.
OMAVDRQPAV.
PhylomeDBQ3IXK6.
ProtClustDBPRK00711.

Enzyme and pathway databases

BioCycRSPH272943:RSP_3113-MONOMER.

Family and domain databases

HAMAPMF_01202. DadA.
[Tree]
InterProIPR023080. D-aa_DH_ssu_DadA.
IPR006076. FAD-dep_OxRdtase.
[Graphical view]
KOK00285.
PfamPF01266. DAO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDADA_RHOS4
AccessionPrimary (citable) accession number: Q3IXK6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 8, 2005
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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