Reviewed, UniProtKB/Swiss-Prot Q3IXK6 (DADA_RHOS4)

Names and origin

Protein names

Recommended name:
    D-amino acid dehydrogenase small subunit
    EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	RHOS4_31600
ORF Names:	RSP_3113

Organism

Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) [Complete proteome] [HAMAP]

Taxonomic identifier

272943 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	436 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity.
Catalytic activity	A D-amino acid + H(2)O + acceptor = a 2-oxo acid + NH(3) + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1.
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the dadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alanine catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW potassium ion transport Inferred from electronic annotation. Source: InterPro
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP cation transmembrane transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 436	436	D-amino acid dehydrogenase small subunit		PRO_1000066112
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q3IXK6-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: CAE52B673FC38B0B	FASTA	436	46,151
	10 20 30 40 50 60 MRIVVLGAGV VGVTSAYELA RAGHEVTVVD RQPAAALETS FANAGEISPG YASPWAAPGI 70 80 90 100 110 120 PAKALRWMFM KHAPLVIRPR LDAAQVRFLL AILRNCTPAA YAQNKGRMVR LAEYSRDCLT 130 140 150 160 170 180 DLRATTGLAF DERQQGTLQL FRSQKQLDAA ARDIEVLRAG GVPFELLDAD GCLAAEPGLR 190 200 210 220 230 240 AARDRIAGGL RLTGDETGDC FKFTQGLAGL AEEGGVRFRY GTGVERLRVE GGRVTGVETT 250 260 270 280 290 300 KGTFLADAVV VALGSHSPAL VAPLGLRLPV YPVKGYSITV PIVDADRAPV STVMDETYKI 310 320 330 340 350 360 AITRLGTRIR VGGMAEVAGF SATLPPARRE TLAMSVNDLF GGAGDLSRAS FWTGLRPMTP 370 380 390 400 410 420 DGTPVVGRTP VAGLWLNTGH GTLGWTMAAG SARVLSDLID GRAPEIESAD LGIERYAAPG 430 RRARPAVRLN PARQAG

References

[1]

"Complete sequence of chromosome 2 of Rhodobacter sphaeroides 2.4.1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000144 Genomic DNA. Translation: ABA80728.1.
RefSeq	YP_354629.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3721388.
GenomeReviews	Gene locus RHOS4_31600 in contig CP000144_GR.
KEGG	rsp:RSP_3113.
NMPDR	fig|272943.3.peg.3123.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3IXK6.
Enzyme and pathway databases
BioCyc	RSPH272943:RSP_3113-MON.
Family and domain databases
HAMAP	MF_01202. [Tree]
InterPro	IPR006076. FAD-dep_OxRdtase. IPR006036. K_uptake_TrkA. [Graphical view]
Pfam	PF01266. DAO. 1 hit. [Graphical view]
PRINTS	PR00335. KUPTAKETRKA.
ProtoNet	Search...

Entry information

Entry name

DADA_RHOS4

Accession

Primary (citable) accession number: Q3IXK6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 8, 2005
Last modified:	November 25, 2008
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)