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Protein
Submitted name:

O-acetylhomoserine aminocarboxypropyltransferase (Methionine synthase)

Gene

metY2

Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. O-acetylhomoserine aminocarboxypropyltransferase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Enzyme and pathway databases

BioCyciNPHA348780:GJX0-141-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
O-acetylhomoserine aminocarboxypropyltransferase (Methionine synthase)Imported (EC:2.5.1.49Imported)
Gene namesi
Name:metY2Imported
Ordered Locus Names:NP_0280AImported
OrganismiNatronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)Imported
Taxonomic identifieri348780 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeNatronomonas
ProteomesiUP000002698: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiQ3IUE9.

Interactioni

Protein-protein interaction databases

STRINGi348780.NP0280A.

Structurei

3D structure databases

ProteinModelPortaliQ3IUE9.
SMRiQ3IUE9. Positions 7-423.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG2873.
HOGENOMiHOG000246417.
KOiK01740.
OMAiEPAYHGV.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR006235. OAc-hSer/O-AcSer_sulfhydrylase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 1 hit.
PTHR11808:SF12. PTHR11808:SF12. 1 hit.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01326. OAH_OAS_sulfhy. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3IUE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDRDDLYTD SLHAGQEADP TTGARAPPIY QTTSYEFDDA EHAADLFGLR
60 70 80 90 100
EAGNIYSRIM NPTNAVLEER IASLEGGVAA LATSSGMASF DLATFILASA
110 120 130 140 150
GDNIVSSSSL YGGTYTYLTH TVERRGVETR FVDTLDYEAY EEAIDEDTAF
160 170 180 190 200
VHCETIGNPA LVTPDLERLA DIAHDNGVPL FVDNTFATPA LCRPLEHGAD
210 220 230 240 250
LVWNSTTKWI HGSGTTVGGV LVDGGSFPWD EHADRFPEIA KPNPAYHGIN
260 270 280 290 300
FSETFGDAAF AYAARTRGLR DLGNQQSPFD AWTTVQGLET LPMRMERHCE
310 320 330 340 350
NAQAVAEFLD DHPEVSWVTY PGLEDHETHE EASEYLDGYG GMITFGLEDG
360 370 380 390 400
YEAARTTVES TELASLLANV GDAKTLIIHP ASTTHQQLTD EEKQASGVTD
410 420
DLVRLSVGLE DTDSIIADLE AAIDEAT
Length:427
Mass (Da):46,361
Last modified:November 8, 2005 - v1
Checksum:iDCD87EAF42C7BCAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR936257 Genomic DNA. Translation: CAI48231.1.
RefSeqiWP_011321870.1. NC_007426.1.
YP_325803.1. NC_007426.1.

Genome annotation databases

EnsemblBacteriaiCAI48231; CAI48231; NP_0280A.
GeneIDi3702921.
KEGGinph:NP0280A.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR936257 Genomic DNA. Translation: CAI48231.1.
RefSeqiWP_011321870.1. NC_007426.1.
YP_325803.1. NC_007426.1.

3D structure databases

ProteinModelPortaliQ3IUE9.
SMRiQ3IUE9. Positions 7-423.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi348780.NP0280A.

Proteomic databases

PRIDEiQ3IUE9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAI48231; CAI48231; NP_0280A.
GeneIDi3702921.
KEGGinph:NP0280A.

Phylogenomic databases

eggNOGiCOG2873.
HOGENOMiHOG000246417.
KOiK01740.
OMAiEPAYHGV.

Enzyme and pathway databases

BioCyciNPHA348780:GJX0-141-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR006235. OAc-hSer/O-AcSer_sulfhydrylase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 1 hit.
PTHR11808:SF12. PTHR11808:SF12. 1 hit.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01326. OAH_OAS_sulfhy. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis."
    Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D.
    Genome Res. 15:1336-1343(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35678 / DSM 2160Imported.

Entry informationi

Entry nameiQ3IUE9_NATPD
AccessioniPrimary (citable) accession number: Q3IUE9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: March 4, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.