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Q3IQ37

- TRPF_NATPD

UniProt

Q3IQ37 - TRPF_NATPD

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciNPHA348780:GJX0-1695-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
    Short name:
    PRAIUniRule annotation
    Gene namesi
    Name:trpFUniRule annotation
    Ordered Locus Names:NP_3340A
    OrganismiNatronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)
    Taxonomic identifieri348780 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeNatronomonas
    ProteomesiUP000002698: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 208208N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000018612Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi348780.NP3340A.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3IQ37.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0135.
    HOGENOMiHOG000161598.
    KOiK01817.
    OMAiETHDWER.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3IQ37-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTRVKVCGIT NRSDLDTAVD AGVDAVGLIV DVDVQTPREI SPQQAAELAA    50
    ATPPFVTAVL VTMADVPDAA TELVEAVRPD AVQVHGESTP DALASLGAAV 100
    EADVIKATDP GTAATYDGHA DAVLVDSLDE SGAGGTGTVH DWDRTGELVE 150
    SLQSPVVLAG GLTPENVADA VEAAAPFAVD VASGVEAESG QKDADAVSAF 200
    VDAAGGCQ 208
    Length:208
    Mass (Da):20,745
    Last modified:November 8, 2005 - v1
    Checksum:i414508A340FAE2D2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR936257 Genomic DNA. Translation: CAI49761.1.
    RefSeqiYP_327316.1. NC_007426.1.

    Genome annotation databases

    EnsemblBacteriaiCAI49761; CAI49761; NP_3340A.
    GeneIDi3703416.
    KEGGinph:NP3340A.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR936257 Genomic DNA. Translation: CAI49761.1 .
    RefSeqi YP_327316.1. NC_007426.1.

    3D structure databases

    ProteinModelPortali Q3IQ37.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 348780.NP3340A.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAI49761 ; CAI49761 ; NP_3340A .
    GeneIDi 3703416.
    KEGGi nph:NP3340A.

    Phylogenomic databases

    eggNOGi COG0135.
    HOGENOMi HOG000161598.
    KOi K01817.
    OMAi ETHDWER.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci NPHA348780:GJX0-1695-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis."
      Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D.
      Genome Res. 15:1336-1343(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35678 / DSM 2160.

    Entry informationi

    Entry nameiTRPF_NATPD
    AccessioniPrimary (citable) accession number: Q3IQ37
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3