Reviewed, UniProtKB/Swiss-Prot Q3IPJ7 (RNP3_NATPD)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 3
      Short name=RNase P component 3
    EC=3.1.26.5

Gene names

Name:	rnp3
Ordered Locus Names:	NP3726A

Organism

Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) [Complete proteome] [HAMAP]

Taxonomic identifier

348780 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Natronomonas

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00756
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	Ribonuclease P protein component 3 HAMAP MF_00756		PRO_1000046630

Sequences

	Sequence		Length	Mass (Da)
	Q3IPJ7-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: CA7EFF4594397539	FASTA	236	25,695
	10 20 30 40 50 60 MYEGVHAHPD GNATVARFAE TAASRGYDGI VVRNHGDAQT DYDADAVAAE YGVEVVSGIE 70 80 90 100 110 120 IRTDDTAQAS GLVGNYRSKR DIVCVHGGEL NRFAVEEPKV DVLAHPMRDG DVNHVLAKAA 130 140 150 160 170 180 AENGVHFEFN FGRVLRADGG KRVQAIQGLR KLRELVDQYD APYVVSADPE SHLELRSSRD 190 200 210 220 230 LAAVGETVGF DREAITDGLA AWADIVERNR RRRSAAVVEP GVRIERADGE TDDSRE

References

[1]	"Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis." Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D. Genome Res. 15:1336-1343(2005) [PubMed: 16169924] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR936257 Genomic DNA. Translation: CAI49954.1.
RefSeq	YP_327506.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q3IPJ7.
Genome annotation databases
GeneID	3703114.
GenomeReviews	Gene locus NP3726A in contig CR936257_GR.
KEGG	nph:NP3726A.
NMPDR	fig|348780.3.peg.2324.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3IPJ7.
OMA	ENPRVDI.
Enzyme and pathway databases
BioCyc	NPHA348780:NP3726A-MON.
Family and domain databases
HAMAP	MF_00756. [Tree]
InterPro	IPR002738. RNase_P_p30. [Graphical view]
Pfam	PF01876. RNase_P_p30. 1 hit. [Graphical view]
ProDom	PD016938. RNase_P_p30_arch. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

RNP3_NATPD

Accession

Primary (citable) accession number: Q3IPJ7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 8, 2005
Last modified:	November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)