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Protein

Ribonuclease P protein component 2

Gene

rnp2

Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processtRNA processing

Enzyme and pathway databases

BioCyciNPHA348780:G1GI2-1860-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 2UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 2UniRule annotation
Alternative name(s):
Pop5UniRule annotation
Gene namesi
Name:rnp2UniRule annotation
Ordered Locus Names:NP_3736A
OrganismiNatronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis)
Taxonomic identifieri348780 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHaloarculaceaeNatronomonas
Proteomesi
  • UP000002698 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001483701 – 161Ribonuclease P protein component 2Add BLAST161

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi348780.NP3736A

Structurei

3D structure databases

ProteinModelPortaliQ3IPJ2
SMRiQ3IPJ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01365 Archaea
COG1369 LUCA
HOGENOMiHOG000092114
KOiK03537
OMAiQRELWYA
OrthoDBiPOG093Z0EPO

Family and domain databases

Gene3Di3.30.70.3250, 1 hit
HAMAPiMF_00755 RNase_P_2, 1 hit
InterProiView protein in InterPro
IPR002759 RNase_P/MRP_subunit
IPR038085 Rnp2-like_sf
PfamiView protein in Pfam
PF01900 RNase_P_Rpp14, 1 hit
SUPFAMiSSF160350 SSF160350, 1 hit

Sequencei

Sequence statusi: Complete.

Q3IPJ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHLPKHLRP RWRYLAVGLE SWPDADIDRR AFQRELWFAA QNLIGDAGSA
60 70 80 90 100
ALDGSVLHFR FEDGDGEAVI RARRGEVDAL RAVLATLSTV DGHPLGVVVR
110 120 130 140 150
GVSGTVRACE EKYIRGPQEG TEERTVAFAG ADRPAVVRND RVTVELSGGP
160
VGATALDIRD N
Length:161
Mass (Da):17,554
Last modified:November 8, 2005 - v1
Checksum:i370AE862D8DD1AD3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR936257 Genomic DNA Translation: CAI49959.1
RefSeqiWP_011323576.1, NC_007426.1

Genome annotation databases

GeneIDi3703113
KEGGinph:NP_3736A

Similar proteinsi

Entry informationi

Entry nameiRNP2_NATPD
AccessioniPrimary (citable) accession number: Q3IPJ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: November 8, 2005
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health