Q3IPJ2 (RNP2_NATPD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 2
Short name=RNase P component 2
EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	NP_3736A

Organism

Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) [Complete proteome] [HAMAP]

Taxonomic identifier

348780 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Natronomonas › Natronomonas pharaonis

Protein attributes

Sequence length	161 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00755
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 161	161	Ribonuclease P protein component 2 HAMAP-Rule MF_00755		PRO_1000148370

Sequences

	Sequence		Length	Mass (Da)
	Q3IPJ2 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 370AE862D8DD1AD3	FASTA	161	17,554
	10 20 30 40 50 60 MKHLPKHLRP RWRYLAVGLE SWPDADIDRR AFQRELWFAA QNLIGDAGSA ALDGSVLHFR 70 80 90 100 110 120 FEDGDGEAVI RARRGEVDAL RAVLATLSTV DGHPLGVVVR GVSGTVRACE EKYIRGPQEG 130 140 150 160 TEERTVAFAG ADRPAVVRND RVTVELSGGP VGATALDIRD N

References

[1]

"Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis." Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D. Genome Res. 15:1336-1343(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 2160 / ATCC 35678.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR936257 Genomic DNA. Translation: CAI49959.1.
RefSeq	YP_327511.1. NC_007426.1.
3D structure databases
ProteinModelPortal	Q3IPJ2.
ModBase	Search...
Protein-protein interaction databases
STRING	348780.NP3736A.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAI49959; CAI49959; NP_3736A.
GeneID	3703113.
KEGG	nph:NP3736A.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1369.
HOGENOM	HOG000092114.
KO	K03537.
OMA	PKHLRPR.
ProtClustDB	CLSK2517860.
Enzyme and pathway databases
BioCyc	NPHA348780:GJX0-1897-MONOMER.
Family and domain databases
HAMAP	MF_00755. RNase_P_2.
InterPro	IPR002759. RNase_P/MRP_subunit. [Graphical view]
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP2_NATPD

Accession

Primary (citable) accession number: Q3IPJ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	November 8, 2005
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program