Q3IPI5 (ACYP_NATPD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	NP3750A

Organism

Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) [Complete proteome] [HAMAP]

Taxonomic identifier

348780 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Natronomonas

Protein attributes

Sequence length	92 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 92	92	Acylphosphatase HAMAP MF_01450		PRO_0000326863
Regions
	Domain	6 – 92	87	Acylphosphatase-like
Sites
	Active site	21	1	By similarity
	Active site	39	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3IPI5 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 971056BAACED48C0	FASTA	92	10,430
	10 20 30 40 50 60 MSDRIRAHVY VSGRVQGVYY RANTRDTARE RDIDGWVRNL DDGRVEAVFE GPREAVESMV 70 80 90 GWCHTGSPKA RVESVDAAYD DPEGVDGFEI RR

References

[1]

"Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis." Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D. Genome Res. 15:1336-1343(2005) [PubMed: 16169924] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 2160 / ATCC 35678.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR936257 Genomic DNA. Translation: CAI49966.1.
RefSeq	YP_327518.1. NC_007426.1.
3D structure databases
HSSP	HSSP built from PDB template 2BJD based on UniProtKB Q97ZL0.
ProteinModelPortal	Q3IPI5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3IPI5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3702491.
GenomeReviews	Gene locus NP3750A in contig CR936257_GR.
KEGG	nph:NP3750A.
NMPDR	fig|348780.3.peg.2336.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG12401.
HOGENOM	HBG750266.
OMA	WCHTGSP.
PhylomeDB	Q3IPI5.
ProtClustDB	PRK14423.
Enzyme and pathway databases
BioCyc	NPHA348780:NP3750A-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR020456. Acylphosphatase. IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PRINTS	PR00112. ACYLPHPHTASE.
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. False negative. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_NATPD

Accession

Primary (citable) accession number: Q3IPI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	November 8, 2005
Last modified:	November 16, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program