Q3IP90 (Q3IP90_NATPD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Name:	purM EMBL CAI50061.1
Ordered Locus Names:	NP3940A

Organism

Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) [Complete proteome] [HAMAP]

Taxonomic identifier

348780 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Natronomonas

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004370 EMBL CAI50061.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3IP90 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: ED5E1C24329AB4B0	FASTA	327	34,668
	10 20 30 40 50 60 MTEDDSEAEG LTYAETGVDI EASEAATAAL LGAVEDFEGD YAGLVDIGDR YLALATDGVG 70 80 90 100 110 120 TKLLVAEALD DYSTIGIDCI AMNANDLIAT GVTPVAFVDY LAVETPDDET AEQVGEGLSE 130 140 150 160 170 180 GAERAEIALL GGETAVMPDV IRGLDLAGAC VGLATEDELF DGEAAAGDYL VGLPSSGIHS 190 200 210 220 230 240 NGLTLAREAV TQRHDYTDPF PYDDDRTIGE VLLEPTRIYR EVLGPLHAAE THAAAHVTGG 250 260 270 280 290 300 GWTNLSRMGE YRYVIEDPFE PQPVFEFVQE EGSVDDEEMH RTFNMGTGFV AALPADDAEA 310 320 VVEELSDARI IGRVEDGDAV EIRGLEL

References

[1]	"Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis." Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D. Genome Res. 15:1336-1343(2005) [PubMed: 16169924] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR936257 Genomic DNA. Translation: CAI50061.1.
RefSeq	YP_327613.1. NC_007426.1.
3D structure databases
ProteinModelPortal	Q3IP90.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3IP90.
Proteomic databases
PRIDE	Q3IP90.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3703074.
GenomeReviews	Gene locus NP3940A in contig CR936257_GR.
KEGG	nph:NP3940A.
NMPDR	fig|348780.3.peg.2543.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04189.
HOGENOM	HBG531222.
OMA	PENIPRV.
PhylomeDB	Q3IP90.
ProtClustDB	PRK05385.
Enzyme and pathway databases
BioCyc	NPHA348780:NP3940A-MONOMER.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3IP90_NATPD

Accession

Primary (citable) accession number: Q3IP90

Entry history

Integrated into UniProtKB/TrEMBL:	November 8, 2005
Last sequence update:	November 8, 2005
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)