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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi8Divalent metal cationUniRule annotation1
Metal bindingi9Divalent metal cationUniRule annotation1
Metal bindingi39Divalent metal cationUniRule annotation1
Metal bindingi87Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandMetal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:NP_4208A
OrganismiNatronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis)
Taxonomic identifieri348780 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHaloarculaceaeNatronomonas
Proteomesi
  • UP000002698 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002356801 – 2575'-nucleotidase SurEAdd BLAST257

Proteomic databases

PRIDEiQ3INV7.

Interactioni

Protein-protein interaction databases

STRINGi348780.NP4208A.

Structurei

3D structure databases

ProteinModelPortaliQ3INV7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02303. Archaea.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiANLGEYV.
OrthoDBiPOG093Z08ZZ.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiView protein in InterPro
IPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
IPR036523. SurE-like_sf.
PfamiView protein in Pfam
PF01975. SurE. 1 hit.
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3INV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVLLTNDDG IDAVGIRALY DALAEVADVT AVAPADDQSA VGRQLSRTVE
60 70 80 90 100
LHDHELGYAV EGTPADCVIA GLGALDLDPD IVVAGCNEGA NLGEYVLGRS
110 120 130 140 150
GTVSAAVEAA FFGVPAIAAS VYFPAGDVTI EEFDPDKTDF AEASRAVRYL
160 170 180 190 200
VDNAIGAGVF DAADYLNVNA PLPPETGHAP MEITEPSHVY EMDGERDGET
210 220 230 240 250
VRIQDHIWER MAEGTIPDPP GTDRRAVVEG RVSVSPLTAP HPTTGHEGLA

GLAEKYQ
Length:257
Mass (Da):26,966
Last modified:November 8, 2005 - v1
Checksum:i3532C616A2073451
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR936257 Genomic DNA. Translation: CAI50195.1.
RefSeqiWP_011323811.1. NC_007426.1.

Genome annotation databases

GeneIDi3703224.
KEGGinph:NP_4208A.

Similar proteinsi

Entry informationi

Entry nameiSURE_NATPD
AccessioniPrimary (citable) accession number: Q3INV7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: November 8, 2005
Last modified: October 25, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families