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Q3IMS0

- G6PI_NATPD

UniProt

Q3IMS0 - G6PI_NATPD

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Protein
Probable glucose-6-phosphate isomerase
Gene
pgi, NP_4992A
Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei269 – 2691Proton donor By similarity
Active sitei290 – 2901 By similarity
Active sitei401 – 4011 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciNPHA348780:GJX0-2532-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:NP_4992A
OrganismiNatronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)
Taxonomic identifieri348780 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeNatronomonas
ProteomesiUP000002698: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 428428Probable glucose-6-phosphate isomeraseUniRule annotation
PRO_0000230944Add
BLAST

Proteomic databases

PRIDEiQ3IMS0.

Interactioni

Protein-protein interaction databases

STRINGi348780.NP4992A.

Structurei

3D structure databases

ProteinModelPortaliQ3IMS0.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100402.
KOiK01810.
OMAiQVIFIGN.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3IMS0-1 [UniParc]FASTAAdd to Basket

« Hide

MNVDFGNALA AEAVTGVSEA SLERLDDRVA DAHDRIEANI EARRFGYASL    50
ALPTDTDPDA IYEAVSGFDP EAVLTVGIGG SALGAETITA ALGAESHYTL 100
DNVDPAPTRQ LLDELPLSST LVNVVSRSGT TAETLANFLV VREAMADAGV 150
DWTDRTVVTT GAEGPLRTLA DAHDLPSCTV PEGVPGRFSA LSAVGLLPAA 200
ALGCDIEAVL AGGAAGRESL APSLFESPAY AYGAVAYATE QRGATTNAIV 250
PYAEQLEPFA EWFAQLWAES LGKDGLGQTP ARALGATDQH SQLQLYRAGR 300
KDKLVTLVRP RERAGVDIPE TDIDALSYLG GESLESLLDA EFEATEASLA 350
AAGQPNVRIE LDSLDAHGVG ELLYGMEAAC ILYGELLGIE TFTQPAVEWG 400
KRAARGLLGG GDFEEAEAVA DKTVRRVE 428
Length:428
Mass (Da):44,803
Last modified:November 8, 2005 - v1
Checksum:i79194EECAC97C7AE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR936257 Genomic DNA. Translation: CAI50587.1.
RefSeqiWP_011324198.1. NC_007426.1.
YP_331220.1. NC_007426.1.

Genome annotation databases

EnsemblBacteriaiCAI50587; CAI50587; NP_4992A.
GeneIDi3703019.
KEGGinph:NP4992A.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR936257 Genomic DNA. Translation: CAI50587.1 .
RefSeqi WP_011324198.1. NC_007426.1.
YP_331220.1. NC_007426.1.

3D structure databases

ProteinModelPortali Q3IMS0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 348780.NP4992A.

Proteomic databases

PRIDEi Q3IMS0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI50587 ; CAI50587 ; NP_4992A .
GeneIDi 3703019.
KEGGi nph:NP4992A.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100402.
KOi K01810.
OMAi QVIFIGN.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci NPHA348780:GJX0-2532-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis."
    Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D.
    Genome Res. 15:1336-1343(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35678 / DSM 2160.

Entry informationi

Entry nameiG6PI_NATPD
AccessioniPrimary (citable) accession number: Q3IMS0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: November 8, 2005
Last modified: September 3, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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