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Q3IMS0

- G6PI_NATPD

UniProt

Q3IMS0 - G6PI_NATPD

Protein

Probable glucose-6-phosphate isomerase

Gene

pgi

Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei269 – 2691Proton donorUniRule annotation
    Active sitei290 – 2901UniRule annotation
    Active sitei401 – 4011UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciNPHA348780:GJX0-2532-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:NP_4992A
    OrganismiNatronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)
    Taxonomic identifieri348780 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeNatronomonas
    ProteomesiUP000002698: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 428428Probable glucose-6-phosphate isomerasePRO_0000230944Add
    BLAST

    Proteomic databases

    PRIDEiQ3IMS0.

    Interactioni

    Protein-protein interaction databases

    STRINGi348780.NP4992A.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3IMS0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100402.
    KOiK01810.
    OMAiQVIFIGN.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3IMS0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNVDFGNALA AEAVTGVSEA SLERLDDRVA DAHDRIEANI EARRFGYASL    50
    ALPTDTDPDA IYEAVSGFDP EAVLTVGIGG SALGAETITA ALGAESHYTL 100
    DNVDPAPTRQ LLDELPLSST LVNVVSRSGT TAETLANFLV VREAMADAGV 150
    DWTDRTVVTT GAEGPLRTLA DAHDLPSCTV PEGVPGRFSA LSAVGLLPAA 200
    ALGCDIEAVL AGGAAGRESL APSLFESPAY AYGAVAYATE QRGATTNAIV 250
    PYAEQLEPFA EWFAQLWAES LGKDGLGQTP ARALGATDQH SQLQLYRAGR 300
    KDKLVTLVRP RERAGVDIPE TDIDALSYLG GESLESLLDA EFEATEASLA 350
    AAGQPNVRIE LDSLDAHGVG ELLYGMEAAC ILYGELLGIE TFTQPAVEWG 400
    KRAARGLLGG GDFEEAEAVA DKTVRRVE 428
    Length:428
    Mass (Da):44,803
    Last modified:November 8, 2005 - v1
    Checksum:i79194EECAC97C7AE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR936257 Genomic DNA. Translation: CAI50587.1.
    RefSeqiWP_011324198.1. NC_007426.1.
    YP_331220.1. NC_007426.1.

    Genome annotation databases

    EnsemblBacteriaiCAI50587; CAI50587; NP_4992A.
    GeneIDi3703019.
    KEGGinph:NP4992A.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR936257 Genomic DNA. Translation: CAI50587.1 .
    RefSeqi WP_011324198.1. NC_007426.1.
    YP_331220.1. NC_007426.1.

    3D structure databases

    ProteinModelPortali Q3IMS0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 348780.NP4992A.

    Proteomic databases

    PRIDEi Q3IMS0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAI50587 ; CAI50587 ; NP_4992A .
    GeneIDi 3703019.
    KEGGi nph:NP4992A.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100402.
    KOi K01810.
    OMAi QVIFIGN.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci NPHA348780:GJX0-2532-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis."
      Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D.
      Genome Res. 15:1336-1343(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35678 / DSM 2160.

    Entry informationi

    Entry nameiG6PI_NATPD
    AccessioniPrimary (citable) accession number: Q3IMS0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3