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Q3IMS0 (G6PI_NATPD) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:NP4992A
OrganismNatronomonas pharaonis (strain DSM 2160 / ATCC 35678) [Complete proteome] [HAMAP]
Taxonomic identifier348780 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Natronomonas

Protein attributes

Sequence length428 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00473

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473

Subcellular location

Cytoplasm By similarity HAMAP MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 428428Probable glucose-6-phosphate isomerase HAMAP MF_00473
PRO_0000230944

Sites

Active site2691Proton donor By similarity
Active site2901 By similarity
Active site4011 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3IMS0 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 79194EECAC97C7AE

FASTA42844,803
        10         20         30         40         50         60 
MNVDFGNALA AEAVTGVSEA SLERLDDRVA DAHDRIEANI EARRFGYASL ALPTDTDPDA 

        70         80         90        100        110        120 
IYEAVSGFDP EAVLTVGIGG SALGAETITA ALGAESHYTL DNVDPAPTRQ LLDELPLSST 

       130        140        150        160        170        180 
LVNVVSRSGT TAETLANFLV VREAMADAGV DWTDRTVVTT GAEGPLRTLA DAHDLPSCTV 

       190        200        210        220        230        240 
PEGVPGRFSA LSAVGLLPAA ALGCDIEAVL AGGAAGRESL APSLFESPAY AYGAVAYATE 

       250        260        270        280        290        300 
QRGATTNAIV PYAEQLEPFA EWFAQLWAES LGKDGLGQTP ARALGATDQH SQLQLYRAGR 

       310        320        330        340        350        360 
KDKLVTLVRP RERAGVDIPE TDIDALSYLG GESLESLLDA EFEATEASLA AAGQPNVRIE 

       370        380        390        400        410        420 
LDSLDAHGVG ELLYGMEAAC ILYGELLGIE TFTQPAVEWG KRAARGLLGG GDFEEAEAVA 


DKTVRRVE

« Hide

References

[1]"Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis."
Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D.
Genome Res. 15:1336-1343(2005) [PubMed: 16169924] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 2160 / ATCC 35678.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR936257 Genomic DNA. Translation: CAI50587.1.
RefSeqYP_331220.1. NC_007426.1.

3D structure databases

ProteinModelPortalQ3IMS0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3IMS0.

Proteomic databases

PRIDEQ3IMS0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3703019.
GenomeReviewsGene locus NP4992A in contig CR936257_GR.
KEGGnph:NP4992A.
NMPDRfig|348780.3.peg.1849.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG05992.
HOGENOMHBG615843.
OMARINDKNS.
ProtClustDBCLSK511579.

Enzyme and pathway databases

BioCycNPHA348780:NP4992A-MONOMER.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
[Tree]
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
KOK01810.
PANTHERPTHR11469. G6P_Isomerase. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_NATPD
AccessionPrimary (citable) accession number: Q3IMS0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: November 8, 2005
Last modified: November 16, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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