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Protein

Putative ribose 1,5-bisphosphate isomerase

Gene

NP_5174A

Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the conversion of ribose 1,5-bisphosphate to ribulose 1,5-bisphosphate (RuBP), the CO2 acceptor and substrate for RubisCO.UniRule annotation

Catalytic activityi

Alpha-D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate.UniRule annotation

Cofactori

NAD+UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi34 – 6229NADUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciNPHA348780:GJX0-2623-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ribose 1,5-bisphosphate isomeraseUniRule annotation (EC:5.3.1.29UniRule annotation)
Alternative name(s):
Ribulose 1,5-bisphosphate synthaseUniRule annotation
Short name:
RuBP synthaseUniRule annotation
Gene namesi
Ordered Locus Names:NP_5174A
OrganismiNatronomonas pharaonis (strain ATCC 35678 / DSM 2160) (Halobacterium pharaonis)
Taxonomic identifieri348780 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeNatronomonas
Proteomesi
  • UP000002698 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309Putative ribose 1,5-bisphosphate isomerasePRO_0000259382Add
BLAST

Proteomic databases

PRIDEiQ3IMI0.

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi348780.NP5174A.

Structurei

3D structure databases

ProteinModelPortaliQ3IMI0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the THI4 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00574. Archaea.
COG1635. LUCA.
HOGENOMiHOG000106048.
KOiK03146.
OMAiGIVMNWT.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00304. Thi4.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR002922. Thi4_fam.
IPR022828. Thi4_putative.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR00292. TIGR00292. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3IMI0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEFDQFSDV GEAEVTRAIG QEWTEEFMDF SDSDVIIVGG GPSGLMAAKE
60 70 80 90 100
LSERGVQTMV VEKNNYLGGG FWLGGFLMNK VTVRDPAQNV LEDLDVDFKR
110 120 130 140 150
SQDSEGLYVA NGPEACSGLI KAACDAGAKM QNMTEFTDIV IREDHRVGGI
160 170 180 190 200
VMNWTPVHAL PREITCVDPI AVEADLVIDA TGHDAVAVSK LQERGVLNAP
210 220 230 240 250
GIEHADEHNT GMDQTGDDSY GAPGHDSPGH DSMWVGQSED AVVEHTGLAH
260 270 280 290 300
EGLIVTGMAT ATTYGLPRMG PTFGAMLLSG KRAAQAALDE LGVDAPDVEM

TTRAEPADD
Length:309
Mass (Da):32,910
Last modified:November 8, 2005 - v1
Checksum:i1D96EC83C65DEB4F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR936257 Genomic DNA. Translation: CAI50678.1.
RefSeqiWP_011324288.1. NC_007426.1.

Genome annotation databases

EnsemblBacteriaiCAI50678; CAI50678; NP_5174A.
GeneIDi3703243.
KEGGinph:NP_5174A.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR936257 Genomic DNA. Translation: CAI50678.1.
RefSeqiWP_011324288.1. NC_007426.1.

3D structure databases

ProteinModelPortaliQ3IMI0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi348780.NP5174A.

Proteomic databases

PRIDEiQ3IMI0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAI50678; CAI50678; NP_5174A.
GeneIDi3703243.
KEGGinph:NP_5174A.

Phylogenomic databases

eggNOGiarCOG00574. Archaea.
COG1635. LUCA.
HOGENOMiHOG000106048.
KOiK03146.
OMAiGIVMNWT.

Enzyme and pathway databases

BioCyciNPHA348780:GJX0-2623-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00304. Thi4.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR002922. Thi4_fam.
IPR022828. Thi4_putative.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR00292. TIGR00292. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis."
    Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D.
    Genome Res. 15:1336-1343(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35678 / DSM 2160.

Entry informationi

Entry nameiRUBPS_NATPD
AccessioniPrimary (citable) accession number: Q3IMI0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 8, 2005
Last modified: January 20, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.