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Q3IMH1 (Q3IMH1_NATPD) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209
Gene names
Name:ipp EMBL CAI50687.1
Synonyms:ppa HAMAP MF_00209
Ordered Locus Names:NP5192A
OrganismNatronomonas pharaonis (strain DSM 2160 / ATCC 35678) [Complete proteome] [HAMAP]
Taxonomic identifier348780 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Natronomonas

Protein attributes

Sequence length179 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209

Subcellular location

Cytoplasm By similarity HAMAP MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00209
   LigandMagnesium HAMAP MF_00209
Metal-binding HAMAP MF_00209
   Molecular functionHydrolase HAMAP MF_00209 EMBL CAI50687.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphate-containing compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioninorganic diphosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding691Magnesium 1 By similarity HAMAP MF_00209
Metal binding741Magnesium 1 By similarity HAMAP MF_00209
Metal binding741Magnesium 2 By similarity HAMAP MF_00209
Metal binding1061Magnesium 1 By similarity HAMAP MF_00209

Sequences

Sequence LengthMass (Da)Tools
Q3IMH1 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 44DF807AC1860735

FASTA17920,628
        10         20         30         40         50         60 
MAGANLWEDL ETGPNAPEEI YAVVECLKGE RNKYEYDKDI PGVMLDRVLH SNVHYPGDYG 

        70         80         90        100        110        120 
FIPQSYYDDE DPFDVLVLVE DQTFPGCIIE ARPVALMKMD DDGEQDDKVI AVPSEDPRYD 

       130        140        150        160        170 
HIEDLEDIPQ QTLDEIDEFF ETYKNLEEGK EVETQGWEDK QAAFDAIEHA QDLYEEHFG

« Hide

References

[1]"Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis."
Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D.
Genome Res. 15:1336-1343(2005) [PubMed: 16169924] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR936257 Genomic DNA. Translation: CAI50687.1.
RefSeqYP_331319.1. NC_007426.1.

3D structure databases

ProteinModelPortalQ3IMH1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3IMH1.

Proteomic databases

PRIDEQ3IMH1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3702872.
GenomeReviewsGene locus NP5192A in contig CR936257_GR.
KEGGnph:NP5192A.
NMPDRfig|348780.3.peg.2056.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG07782.
HOGENOMHBG529150.
OMAPNDFNVI.
PhylomeDBQ3IMH1.
ProtClustDBCLSK511023.

Enzyme and pathway databases

BioCycNPHA348780:NP5192A-MONOMER.

Family and domain databases

HAMAPMF_00209. Inorganic_PPase.
[Tree]
InterProIPR008162. Pyrophosphatase.
[Graphical view]
Gene3DG3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KOK01507.
PANTHERPTHR10286. Pyrophosphatase. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3IMH1_NATPD
AccessionPrimary (citable) accession number: Q3IMH1
Entry history
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: November 16, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info