Q3ILL7 (PGK_PSEHT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglycerate kinase
EC=2.7.2.3

Gene names

Name:	pgk
Ordered Locus Names:	PSHAa0595

Organism

Pseudoalteromonas haloplanktis (strain TAC 125) [Complete proteome] [HAMAP]

Taxonomic identifier

326442 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas › Pseudoalteromonas haloplanktis

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00145
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00145.
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 391	391	Phosphoglycerate kinase HAMAP-Rule MF_00145		PRO_1000058039
Regions
	Nucleotide binding	345 – 348	4	ATP By similarity
	Region	21 – 23	3	Substrate binding By similarity
	Region	59 – 62	4	Substrate binding By similarity
Sites
	Binding site	36	1	Substrate By similarity
	Binding site	113	1	Substrate By similarity
	Binding site	146	1	Substrate By similarity
	Binding site	197	1	ATP By similarity
	Binding site	319	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3ILL7 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: CA02D13D81F6B3CC	FASTA	391	41,141
	10 20 30 40 50 60 MSVIKMADLD LNGKRVLIRE DLNVPVKAGK VTSDARIRAA LPTIKLALEK GAKVMVMSHL 70 80 90 100 110 120 GRPTEGEYDE EFSLAPVVNY LNDALEQTVR LEKDYLNGVE LADNEVVVFE NVRFNKGEKN 130 140 150 160 170 180 NDEALSKQLA ALCDVYVMDA FGTAHRAQAS THGVGLFADV ACAGPLLSAE LEALGKALDN 190 200 210 220 230 240 PARPLVAIVG GSKVSTKLTV LDSLSKIVDQ LVTGGGIANT FIAAAGYPVG KSLYEADLMD 250 260 270 280 290 300 EANRLCAAAV ANNGEIPVPT DVVVGNEFSD SAVATLKDVS EVTSDDMIFD IGPDTANKLA 310 320 330 340 350 360 KIIANAGTVV WNGPVGVFEF DQFGNGTRAI AQAIANSNAF SIAGGGDTLA AIDKYGISDK 370 380 390 ISYISTGGGA FLEFLEGKKL PAVEMLESRA K

References

[1]

"Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125." Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N., Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G., Ho C., Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C. , Rouy Z., Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A. Genome Res. 15:1325-1335(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TAC 125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR954246 Genomic DNA. Translation: CAI85681.1.
RefSeq	YP_339124.1. NC_007481.1.
3D structure databases
ProteinModelPortal	Q3ILL7.
SMR	Q3ILL7. Positions 2-391.
ModBase	Search...
Protein-protein interaction databases
STRING	326442.PSHAa0595.
Proteomic databases
PRIDE	Q3ILL7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAI85681; CAI85681; PSHAa0595.
GeneID	3709134.
KEGG	pha:PSHAa0595.
PATRIC	32294719. VBIPseHal105694_0560.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0126.
HOGENOM	HOG000227107.
KO	K00927.
OMA	KFGLADK.
ProtClustDB	PRK00073.
Enzyme and pathway databases
BioCyc	PHAL326442:GJIU-606-MONOMER.
UniPathway	UPA00109; UER00185.
Family and domain databases
Gene3D	3.40.50.1260. 1 hit. 3.40.50.1270. 1 hit.
HAMAP	MF_00145. Phosphoglyc_kinase.
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
PANTHER	PTHR11406. PTHR11406. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PIRSF	PIRSF000724. Pgk. 1 hit.
PRINTS	PR00477. PHGLYCKINASE.
SUPFAM	SSF53748. PGK. 1 hit.
PROSITE	PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGK_PSEHT

Accession

Primary (citable) accession number: Q3ILL7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 8, 2005
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program