SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q3IIW8

- LPXB_PSEHT

UniProt

Q3IIW8 - LPXB_PSEHT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Lipid-A-disaccharide synthase
Gene
lpxB, PSHAa2017
Organism
Pseudoalteromonas haloplanktis (strain TAC 125)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciPHAL326442:GJIU-2069-MONOMER.
UniPathwayiUPA00359; UER00481.

Protein family/group databases

CAZyiGT19. Glycosyltransferase Family 19.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthase (EC:2.4.1.182)
Gene namesi
Name:lpxB
Ordered Locus Names:PSHAa2017
OrganismiPseudoalteromonas haloplanktis (strain TAC 125)
Taxonomic identifieri326442 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
ProteomesiUP000006843: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 385385Lipid-A-disaccharide synthaseUniRule annotation
PRO_0000255206Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi326442.PSHAa2017.

Structurei

3D structure databases

ProteinModelPortaliQ3IIW8.

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000018003.
KOiK00748.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3IIW8-1 [UniParc]FASTAAdd to Basket

« Hide

MNKDQKQLRI GIVAGELSGD ILGEGLIKAL KKHFPDAIFE GIAGPKMQAQ    50
GCNTLYDMDE LSVMGLVEVL GRLPRLLKIR KQLVQHFIDN PPDVFIGIDA 100
PDFNLRVEKP LKDAGIKTVQ YVSPSVWAWR EKRIHTISAA TNLVLALLPF 150
EKEFYDKHQV PCTFVGHTLA DDIALEHDDS KARKELGLSP DDKVLALLPG 200
SRGSEVGLLS ETYIKTAVQL QAQNPALKIV VPLVNAKRKA QFTEILNATA 250
PTLKISLLDG QSKQAMQAAD AILLASGTAT LEGMLYKKPM VVGYKIKPLS 300
YWIFKTLFTF NIKYFSLPNL LADEELVPEF LQSECNVANL TQALTPMLNT 350
DNQALKARFL AIHKKIRLNA SEQAANAVAE LINAN 385
Length:385
Mass (Da):42,491
Last modified:November 8, 2005 - v1
Checksum:i5EB17FDA1F34F8B2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR954246 Genomic DNA. Translation: CAI87073.1.
RefSeqiWP_011328675.1. NC_007481.1.
YP_340516.1. NC_007481.1.

Genome annotation databases

EnsemblBacteriaiCAI87073; CAI87073; PSHAa2017.
GeneIDi3710256.
KEGGipha:PSHAa2017.
PATRICi32297631. VBIPseHal105694_1944.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR954246 Genomic DNA. Translation: CAI87073.1 .
RefSeqi WP_011328675.1. NC_007481.1.
YP_340516.1. NC_007481.1.

3D structure databases

ProteinModelPortali Q3IIW8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326442.PSHAa2017.

Protein family/group databases

CAZyi GT19. Glycosyltransferase Family 19.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI87073 ; CAI87073 ; PSHAa2017 .
GeneIDi 3710256.
KEGGi pha:PSHAa2017.
PATRICi 32297631. VBIPseHal105694_1944.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000018003.
KOi K00748.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci PHAL326442:GJIU-2069-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TAC 125.

Entry informationi

Entry nameiLPXB_PSEHT
AccessioniPrimary (citable) accession number: Q3IIW8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 8, 2005
Last modified: September 3, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi